TY - JOUR
AU - Zenclussen, Ana Claudia
AU - Hämmerling, Günter
TI - Cellular Regulation of the Uterine Microenvironment That Enables Embryo Implantation.
JO - Frontiers in immunology
VL - 6
SN - 1664-3224
CY - Lausanne
PB - Frontiers Media
M1 - DKFZ-2017-03866
SP - 321
PY - 2015
AB - Implantation of the fertilized egg into the maternal uterus is a crucial step in pregnancy establishment. Increasing evidence suggests that its success depends on various cell types of the innate immune system and on the fine balance between inflammatory and anti-inflammatory processes. In addition, it has recently been established that regulatory T cells play a superordinate role in dictating the quality of uterine environment required for successful pregnancy. Here, we discuss the cellular regulation of uterine receptivity with emphasis on the function and regulation of cells from the innate and adaptive immune system.
LB - PUB:(DE-HGF)16
C6 - pmid:26136750
C2 - pmc:PMC4470084
DO - DOI:10.3389/fimmu.2015.00321
UR - https://inrepo02.dkfz.de/record/127844
ER -