Home > Publications database > Evaluation of the ESUR PI-RADS scoring system for multiparametric MRI of the prostate with targeted MR/TRUS fusion-guided biopsy at 3.0 Tesla. > print

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024 7 _ |a 10.1007/s00330-013-3017-5
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024 7 _ |a 0938-7994
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024 7 _ |a 1432-1084
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024 7 _ |a 1613-3749
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024 7 _ |a 1613-3757
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037 _ _ |a DKFZ-2017-04180
041 _ _ |a eng
082 _ _ |a 610
100 1 _ |a Röthke, Matthias
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245 _ _ |a Evaluation of the ESUR PI-RADS scoring system for multiparametric MRI of the prostate with targeted MR/TRUS fusion-guided biopsy at 3.0 Tesla.
260 _ _ |a Berlin
|c 2014
|b Springer
336 7 _ |a article
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520 _ _ |a To evaluate the Prostate Imaging Reporting and Data System (PI-RADS) proposed by the European Society of Urogenital Radiology (ESUR) for detection of prostate cancer (PCa) by multiparametric magnetic resonance imaging (mpMRI) in a consecutive cohort of patients with magnetic resonance/transrectal ultrasound (MR/TRUS) fusion-guided biopsy.Suspicious lesions on mpMRI at 3.0 T were scored according to the PI-RADS system before MR/TRUS fusion-guided biopsy and correlated to histopathology results. Statistical correlation was obtained by a Mann-Whitney U test. Receiver operating characteristics (ROC) and optimal thresholds were calculated.In 64 patients, 128/445 positive biopsy cores were obtained out of 95 suspicious regions of interest (ROIs). PCa was present in 27/64 (42%) of the patients. ROC results for the aggregated PI-RADS scores exhibited higher areas under the curve compared to those of the Likert score. Sensitivity/Specificity for the following thresholds were calculated: 85 %/73 % and 67 %/92 % for PI-RADS scores of 9 and 10, respectively; 85 %/60 % and 56 %/97 % for Likert scores of 3 and 4, respectively [corrected.The standardised ESUR PI-RADS system is beneficial to indicate the likelihood of PCa of suspicious lesions on mpMRI. It is also valuable to identify locations to be targeted with biopsy. The aggregated PI-RADS score achieved better results compared to the single five-point Likert score.• The ESUR PI-RADS scoring system was evaluated using multiparametric 3.0-T MRI. • To investigate suspicious findings, transperineal MR/TRUS fusion-guided biopsy was used. • PI-RADS can guide biopsy locations and improve detection of clinically significant cancer. • Biopsy procedures can be optimised, reducing unnecessary negative biopsies for patients. • The PI-RADS scoring system may contribute to more effective prostate MRI.
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700 1 _ |a Kuru, T. H.
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700 1 _ |a Schultze, S.
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700 1 _ |a Tichy, D.
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700 1 _ |a Kopp-Schneider, A.
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700 1 _ |a Fenchel, M.
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700 1 _ |a Schlemmer, Heinz-Peter
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700 1 _ |a Hadaschik, B. A.
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773 _ _ |a 10.1007/s00330-013-3017-5
|g Vol. 24, no. 2, p. 344 - 352
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|t European radiology
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