%0 Journal Article
%A Bickelhaupt, S.
%A Paech, D.
%A Laun, Frederik
%A Steudle, F.
%A Kuder, T. A.
%A Mlynarska, A.
%A Bach, M.
%A Lederer, W.
%A Teiner, S.
%A Schneider, S.
%A Ladd, Mark
%A Daniel, H.
%A Stieber, A.
%A Kopp-Schneider, A.
%A Delorme, S.
%A Schlemmer, H-P
%T Maximum intensity breast diffusion MRI for BI-RADS 4 lesions detected on X-ray mammography.
%J Clinical radiology
%V 72
%N 10
%@ 0009-9260
%C Amsterdam
%I Elsevier Science
%M DKFZ-2017-04327
%P 900.e1 - 900.e8
%D 2017
%X To investigate an abbreviated, contrast-agent free diffusion-weighted (DW) breast magnetic resonance imaging (MRI) protocol that provides a single image for the radiologist to read in order to non-invasively examine Breast Imaging-Reporting and Data System (BI-RADS) 4 lesions detected using breast cancer screening X-ray mammography.This retrospective evaluation within a institutional review board-approved, prospective study included 115 women (mean 57 years, range 50-69 years) with BI-RADS 4 findings on X-ray mammography and indication for biopsy over a period of 15 months. Full diagnostic breast MRI (FDP) was performed prior to biopsy (1.5 T). Maximum intensity breast diffusion (MIBD) images were generated from DW images (b = 1,500 mm/s(2), 3 mm section thickness) of the breast. MIBD and T2-weighted (T2W) images were read by two radiologists and compared to the diagnostic accuracy of an expert reading of the FDP with histopathology as the reference standard. The acquisition time of MIBD and T2W MRI was about 7 minutes.MIBD MRI provided a diagnostic accuracy of 87.93
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:28687167
%R 10.1016/j.crad.2017.05.017
%U https://inrepo02.dkfz.de/record/128310