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@ARTICLE{Weber:128504,
      author       = {T. F. Weber and T. Müller and A. Biesdorf and S. Wörz$^*$
                      and F. Rengier and T. Heye and T. Holland-Letz$^*$ and K.
                      Rohr$^*$ and H.-U. Kauczor and H. von Tengg-Kobligk$^*$},
      title        = {{T}rue four-dimensional analysis of thoracic aortic
                      displacement and distension using model-based segmentation
                      of computed tomography angiography.},
      journal      = {The international journal of cardiovascular imaging},
      volume       = {30},
      number       = {1},
      issn         = {1573-0743},
      address      = {Dordrecht [u.a.]},
      publisher    = {Springer},
      reportid     = {DKFZ-2017-04520},
      pages        = {185 - 194},
      year         = {2014},
      abstract     = {Previous analyses of aortic displacement and distension
                      using computed tomography angiography (CTA) were performed
                      on double-oblique multi-planar reformations and did not
                      consider through-plane motion. The aim of this study was to
                      overcome this limitation by using a novel computational
                      approach for the assessment of thoracic aortic displacement
                      and distension in their true four-dimensional extent. Vessel
                      segmentation with landmark tracking was executed on CTA of
                      24 patients without evidence of aortic disease. Distension
                      magnitudes and maximum displacement vectors (MDV) including
                      their direction were analyzed at 5 aortic locations: left
                      coronary artery (COR), mid-ascending aorta (ASC),
                      brachiocephalic trunk (BCT), left subclavian artery (LSA),
                      descending aorta (DES). Distension was highest for COR (2.3
                      ± 1.2 mm) and BCT (1.7 ± 1.1 mm) compared with ASC, LSA,
                      and DES (p < 0.005). MDV decreased from COR to LSA (p <
                      0.005) and was highest for COR (6.2 ± 2.0 mm) and ASC (3.8
                      ± 1.9 mm). Displacement was directed towards left and
                      anterior at COR and ASC. Craniocaudal displacement at COR
                      and ASC was 1.3 ± 0.8 and 0.3 ± 0.3 mm. At BCT, LSA, and
                      DES no predominant displacement direction was observable.
                      Vessel displacement and wall distension are highest in the
                      ascending aorta, and ascending aortic displacement is
                      primarily directed towards left and anterior. Craniocaudal
                      displacement remains low even close to the left cardiac
                      ventricle.},
      cin          = {B080 / C060 / E010},
      ddc          = {610},
      cid          = {I:(DE-He78)B080-20160331 / I:(DE-He78)C060-20160331 /
                      I:(DE-He78)E010-20160331},
      pnm          = {315 - Imaging and radiooncology (POF3-315)},
      pid          = {G:(DE-HGF)POF3-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:24135852},
      doi          = {10.1007/s10554-013-0307-6},
      url          = {https://inrepo02.dkfz.de/record/128504},
}