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@ARTICLE{Ihle:128817,
      author       = {A. Ihle and U. Mons$^*$ and L. Perna$^*$ and M. Oris and D.
                      Fagot and R. Gabriel and M. Kliegel},
      title        = {{T}he {R}elation of {O}besity to {P}erformance in {V}erbal
                      {A}bilities, {P}rocessing {S}peed, and {C}ognitive
                      {F}lexibility in {O}ld {A}ge: {T}he {R}ole of {C}ognitive
                      {R}eserve.},
      journal      = {Dementia and geriatric cognitive disorders},
      volume       = {42},
      number       = {1-2},
      issn         = {1421-9824},
      address      = {Basel},
      publisher    = {Karger},
      reportid     = {DKFZ-2017-04830},
      pages        = {117 - 126},
      year         = {2016},
      abstract     = {The present study set out to investigate the relation of
                      obesity to performance in verbal abilities, processing
                      speed, and cognitive flexibility and its interplay with key
                      correlates of cognitive reserve in a large sample of older
                      adults.A total of 2,812 older adults served as a sample for
                      the present study. Psychometric tests on verbal abilities,
                      processing speed, and cognitive flexibility were
                      administered. In addition, individuals were interviewed on
                      their weight and height (to calculate body mass index; BMI),
                      educational attainment, occupation, and engaging in
                      different activities throughout adulthood.Obesity (BMI
                      ≥30) was significantly associated with a lower performance
                      in verbal abilities, processing speed, and cognitive
                      flexibility. Moderation analyses showed that obesity was
                      related to lower processing speed and cognitive flexibility
                      only in individuals with low engagement in activities and
                      low education. Hierarchical regression analyses showed that
                      obesity was not related to any of the three investigated
                      cognitive performance measures when cognitive reserve in
                      early and midlife was taken into account.Present data
                      suggest that cognitive reserve accumulated during the life
                      course may reduce the detrimental influences of obesity on
                      cognitive functioning in old age.},
      cin          = {M050 / C060},
      ddc          = {610},
      cid          = {I:(DE-He78)M050-20160331 / I:(DE-He78)C060-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:27632695},
      doi          = {10.1159/000448916},
      url          = {https://inrepo02.dkfz.de/record/128817},
}