%0 Journal Article
%A Kessel, Kerstin A
%A Jäger, Andreas
%A Habermehl, Daniel
%A Rüppell, Jan
%A Bendl, Rolf
%A Debus, Jürgen
%A Combs, Stephanie E
%T Changes in Gross Tumor Volume and Organ Motion Analysis During Neoadjuvant Radiochemotherapy in Patients With Locally Advanced Pancreatic Cancer Using an In-House Analysis System.
%J Technology in cancer research & treatment
%V 15
%N 2
%@ 1533-0338
%C [Thousand Oaks, CA]
%I Sage
%M DKFZ-2017-04896
%P 348 - 354
%D 2016
%X During radiation treatment, movement of the target and organs at risks as well as tumor response can significantly influence dose distribution. This is highly relevant in patients with pancreatic cancer, where organs at risk lie in close proximity to the target.Data sets of 10 patients with locally advanced pancreatic cancer were evaluated. Gross tumor volume deformation was analyzed. Dose changes to organs at risk were determined with focus on kidneys both without adaptive radiotherapy compensation and with replanning based on weekly acquired computed tomography scans.During irradiation, gross tumor volume changes between 0
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:25824268
%R 10.1177/1533034615577515
%U https://inrepo02.dkfz.de/record/128883