TY  - JOUR
AU  - Merz, Maximilian
AU  - Hielscher, Thomas
AU  - Seckinger, Anja
AU  - Hose, Dirk
AU  - Mai, Elias K
AU  - Raab, Marc-Steffen
AU  - Goldschmidt, Hartmut
AU  - Jauch, Anna
AU  - Hillengass, Jens
TI  - Baseline characteristics, chromosomal alterations, and treatment affecting prognosis of deletion 17p in newly diagnosed myeloma.
JO  - American journal of hematology
VL  - 91
IS  - 11
SN  - 0361-8609
CY  - New York, NY
PB  - Wiley-Liss
M1  - DKFZ-2017-05241
SP  - E473 - E477
PY  - 2016
AB  - Deletion 17p13, del(17p), is associated with poor outcome in myeloma but some patients show long-term survival. With the current study we intended to identify factors impacting outcome of such high risk patients. We analyzed 110 newly diagnosed, symptomatic patients with del(17p) detected by fluorescence in situ hybridization (FISH) in CD138-purified myeloma cells to identify prognostic factors for survival. Age >65 years, ISS III, and elevated LDH negatively impacted survival. Patients with subclonal (10-60
LB  - PUB:(DE-HGF)16
C6  - pmid:27508939
DO  - DOI:10.1002/ajh.24533
UR  - https://inrepo02.dkfz.de/record/129236
ER  -