%0 Journal Article
%A Sahm, Felix
%A Schrimpf, Daniel
%A Olar, Adriana
%A Koelsche, Christian
%A Reuss, David
%A Bissel, Juliane
%A Kratz, Annekathrin
%A Capper, David
%A Schefzyk, Sebastian
%A Hielscher, Thomas
%A Wang, Qianghu
%A Sulman, Erik P
%A Adeberg, Sebastian
%A Koch, Arend
%A Okuducu, Ali Fuat
%A Brehmer, Stefanie
%A Schittenhelm, Jens
%A Becker, Albert
%A Brokinkel, Benjamin
%A Schmidt, Melissa
%A Ull, Theresa
%A Gousias, Konstantinos
%A Kessler, Almuth Friederike
%A Lamszus, Katrin
%A Debus, Jürgen
%A Mawrin, Christian
%A Kim, Yoo-Jin
%A Simon, Matthias
%A Ketter, Ralf
%A Paulus, Werner
%A Aldape, Kenneth D
%A Herold-Mende, Christel
%A von Deimling, Andreas
%T TERT Promoter Mutations and Risk of Recurrence in Meningioma.
%J Journal of the National Cancer Institute
%V 108
%N 5
%@ 1460-2105
%C Oxford
%I Oxford Univ. Press
%M DKFZ-2017-05543
%P djv377 -
%D 2016
%X The World Health Organization (WHO) classification and grading system attempts to predict the clinical course of meningiomas based on morphological parameters. However, because of high interobserver variation of some criteria, more reliable prognostic markers are required. Here, we assessed the TERT promoter for mutations in the hotspot regions C228T and C250T in meningioma samples from 252 patients. Mutations were detected in 16 samples (6.4
%K Biomarkers, Tumor (NLM Chemicals)
%K TERT protein, human (NLM Chemicals)
%K Telomerase (NLM Chemicals)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:26668184
%2 pmc:PMC4849806
%R 10.1093/jnci/djv377
%U https://inrepo02.dkfz.de/record/130464