TY  - JOUR
AU  - Sahm, Felix
AU  - Schrimpf, Daniel
AU  - Olar, Adriana
AU  - Koelsche, Christian
AU  - Reuss, David
AU  - Bissel, Juliane
AU  - Kratz, Annekathrin
AU  - Capper, David
AU  - Schefzyk, Sebastian
AU  - Hielscher, Thomas
AU  - Wang, Qianghu
AU  - Sulman, Erik P
AU  - Adeberg, Sebastian
AU  - Koch, Arend
AU  - Okuducu, Ali Fuat
AU  - Brehmer, Stefanie
AU  - Schittenhelm, Jens
AU  - Becker, Albert
AU  - Brokinkel, Benjamin
AU  - Schmidt, Melissa
AU  - Ull, Theresa
AU  - Gousias, Konstantinos
AU  - Kessler, Almuth Friederike
AU  - Lamszus, Katrin
AU  - Debus, Jürgen
AU  - Mawrin, Christian
AU  - Kim, Yoo-Jin
AU  - Simon, Matthias
AU  - Ketter, Ralf
AU  - Paulus, Werner
AU  - Aldape, Kenneth D
AU  - Herold-Mende, Christel
AU  - von Deimling, Andreas
TI  - TERT Promoter Mutations and Risk of Recurrence in Meningioma.
JO  - Journal of the National Cancer Institute
VL  - 108
IS  - 5
SN  - 1460-2105
CY  - Oxford
PB  - Oxford Univ. Press
M1  - DKFZ-2017-05543
SP  - djv377 -
PY  - 2016
AB  - The World Health Organization (WHO) classification and grading system attempts to predict the clinical course of meningiomas based on morphological parameters. However, because of high interobserver variation of some criteria, more reliable prognostic markers are required. Here, we assessed the TERT promoter for mutations in the hotspot regions C228T and C250T in meningioma samples from 252 patients. Mutations were detected in 16 samples (6.4
KW  - Biomarkers, Tumor (NLM Chemicals)
KW  - TERT protein, human (NLM Chemicals)
KW  - Telomerase (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:26668184
C2  - pmc:PMC4849806
DO  - DOI:10.1093/jnci/djv377
UR  - https://inrepo02.dkfz.de/record/130464
ER  -