TY  - JOUR
AU  - von Bueren, André O
AU  - Kortmann, Rolf-Dieter
AU  - von Hoff, Katja
AU  - Friedrich, Carsten
AU  - Mynarek, Martin
AU  - Müller, Klaus
AU  - Goschzik, Tobias
AU  - Zur Mühlen, Anja
AU  - Gerber, Nicolas
AU  - Warmuth-Metz, Monika
AU  - Soerensen, Niels
AU  - Deinlein, Frank
AU  - Benesch, Martin
AU  - Zwiener, Isabella
AU  - Kwiecien, Robert
AU  - Faldum, Andreas
AU  - Bode, Udo
AU  - Fleischhack, Gudrun
AU  - Hovestadt, Volker
AU  - Kool, Marcel
AU  - Jones, David
AU  - Northcott, Paul
AU  - Kuehl, Joachim
AU  - Pfister, Stefan
AU  - Pietsch, Torsten
AU  - Rutkowski, Stefan
TI  - Treatment of Children and Adolescents With Metastatic Medulloblastoma and Prognostic Relevance of Clinical and Biologic Parameters.
JO  - Journal of clinical oncology
VL  - 34
IS  - 34
SN  - 1527-7755
CY  - Alexandria, Va.
PB  - American Society of Clinical Oncology
M1  - DKFZ-2017-05814
SP  - 4151 - 4160
PY  - 2016
AB  - Purpose To assess an intensified treatment in the context of clinical and biologic risk factors in metastatic medulloblastoma. Patients and Methods Patients (4 to 21 years old, diagnosed between 2001 and 2007) received induction chemotherapy, dose-escalated hyperfractionated craniospinal radiotherapy, and maintenance chemotherapy. Subgroup status and other biologic parameters were assessed. Results In 123 eligible patients (median age, 8.2 years old; median follow-up, 5.38 years), 5-year event-free survival (EFS) and overall survival (OS) were 62
LB  - PUB:(DE-HGF)16
C6  - pmid:27863192
DO  - DOI:10.1200/JCO.2016.67.2428
UR  - https://inrepo02.dkfz.de/record/130736
ER  -