TY  - JOUR
AU  - Hahn, Juliane
AU  - Bruder, Herbert
AU  - Rohkohl, Christopher
AU  - Allmendinger, Thomas
AU  - Stierstorfer, Karl
AU  - Flohr, Thomas
AU  - Kachelriess, Marc
TI  - Motion compensation in the region of the coronary arteries based on partial angle reconstructions from short-scan CT data.
JO  - Medical physics
VL  - 44
IS  - 11
SN  - 0094-2405
CY  - New York, NY
M1  - DKFZ-2017-05864
SP  - 5795 - 5813
PY  - 2017
AB  - In order to mitigate motion-induced artifacts, several motion compensation (MoCo) methods have been developed, which are either able to (a) compensate for severe artifacts, but utilize the data for the reconstruction of several cardiac phases, or (b) improve image quality of a single reconstruction with only moderate motion artifacts. We propose a method combining both benefits: dose efficiency by utilizing only the data needed for a single short-scan reconstruction while still being able to compensate for severe artifacts.We introduce a MoCo method, which we call PAMoCo, to improve the visualization of the coronary arteries of a standard coronary CT angiography exam by reducing motion artifacts. As a first step, we segment a region of interest covering a chosen coronary artery. We subdivide a volume covering the whole heart into several stacks, which are sub-volumes, reconstructed from phase-correlated short-scan data acquired during different heart cycles. Motion-compensated reconstruction is performed for each stack separately, based on partial angle reconstructions, which are derived by dividing the data corresponding to the segmented stack volume into several double-overlapping sectors. We model motion along the coronary artery center line obtained from segmentation and the temporal dimension by a low-degree polynomial and create a dense 3D motion vector field (MVF). The parameters defining the MVF are estimated by optimizing an image artifact measuring cost function and we employ a semi-global optimization routine by re-initializing the optimization multiple times. The algorithm was evaluated on the basis of a phantom measurement and clinical data. For the phantom measurement an artificial vessel equipped with calcified lesions mounted on a moving robot arm was measured, where typical coronary artery motion patterns for 70 bpm and 90 bpm have been applied. For analysis, we calculated the calcified volume V inside an ROI and measured the maximum vessel diameter d based on cross-sectional views to compare the performances of standard reconstructions obtained via filtered backprojection (FBP) and PAMoCo reconstructions between 20
LB  - PUB:(DE-HGF)16
C6  - pmid:28801918
DO  - DOI:10.1002/mp.12514
UR  - https://inrepo02.dkfz.de/record/130786
ER  -