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000130923 1001_ $$0P:(DE-He78)60b584aeef81e4c57fd111fa63779b73$$aWiskemann, Joachim$$b0$$eFirst author$$udkfz
000130923 245__ $$aEffects of 12-week resistance training during radiotherapy in breast cancer patients.
000130923 260__ $$aOxford [u.a.]$$bWiley-Blackwell$$c2017
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000130923 520__ $$aExercise is considered to be an effective supportive treatment approach in breast cancer (BC) patients. We conducted a randomized controlled trial to assess the efficacy of a 12-week PRT during radiotherapy. Strength performance was assessed by maximal isokinetic peak torque (MIPT) in two different angular velocities (60°/s and 180°/s) and maximal voluntary isometric contraction for shoulder external and internal rotation, as well as for knee extension and flexion were assessed pre- and post-intervention in 146 patients randomized to PRT or a control group. Statistical analyses were based on analysis of covariance models for the individual changes from baseline to week 13. Intention-to-treat analyses showed significant between-group differences favoring the exercise group (EX) for MIPT in knee flexion and shoulder internal and external rotation (P < 0.05). Subgroup analyses showed borderline significant differences with regard to pretreatment history, revealing that pretreated chemotherapy patients tend to benefit more from PRT than patients without chemotherapy (P = 0.06). Strength gain at the operated arm was significantly higher than at the non-operated arm in EX. PRT was efficacious in increasing upper and lower limb strength in BC patients undergoing adjuvant radiotherapy. Patients with restrictions due to breast cancer-related surgery and pretreated with chemotherapy might benefit the most.
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000130923 7001_ $$0P:(DE-He78)2def8f8594c8f797f5ed4398258c6cac$$aSchmidt, Martina$$b1$$udkfz
000130923 7001_ $$0P:(DE-HGF)0$$aKlassen, O.$$b2
000130923 7001_ $$aDebus, J.$$b3
000130923 7001_ $$aUlrich, C. M.$$b4
000130923 7001_ $$aPotthoff, K.$$b5
000130923 7001_ $$0P:(DE-He78)a0c2037d9054be26907a05ae520d5756$$aSteindorf, Karen$$b6$$eLast author$$udkfz
000130923 773__ $$0PERI:(DE-600)2025503-2$$a10.1111/sms.12777$$gVol. 27, no. 11, p. 1500 - 1510$$n11$$p1500 - 1510$$tScandinavian journal of medicine & science in sports$$v27$$x0905-7188$$y2017
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