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| 001 | 130923 | ||
| 005 | 20240228145558.0 | ||
| 024 | 7 | _ | |a 10.1111/sms.12777 |2 doi |
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| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Wiskemann, Joachim |0 P:(DE-He78)60b584aeef81e4c57fd111fa63779b73 |b 0 |e First author |u dkfz |
| 245 | _ | _ | |a Effects of 12-week resistance training during radiotherapy in breast cancer patients. |
| 260 | _ | _ | |a Oxford [u.a.] |c 2017 |b Wiley-Blackwell |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 520 | _ | _ | |a Exercise is considered to be an effective supportive treatment approach in breast cancer (BC) patients. We conducted a randomized controlled trial to assess the efficacy of a 12-week PRT during radiotherapy. Strength performance was assessed by maximal isokinetic peak torque (MIPT) in two different angular velocities (60°/s and 180°/s) and maximal voluntary isometric contraction for shoulder external and internal rotation, as well as for knee extension and flexion were assessed pre- and post-intervention in 146 patients randomized to PRT or a control group. Statistical analyses were based on analysis of covariance models for the individual changes from baseline to week 13. Intention-to-treat analyses showed significant between-group differences favoring the exercise group (EX) for MIPT in knee flexion and shoulder internal and external rotation (P < 0.05). Subgroup analyses showed borderline significant differences with regard to pretreatment history, revealing that pretreated chemotherapy patients tend to benefit more from PRT than patients without chemotherapy (P = 0.06). Strength gain at the operated arm was significantly higher than at the non-operated arm in EX. PRT was efficacious in increasing upper and lower limb strength in BC patients undergoing adjuvant radiotherapy. Patients with restrictions due to breast cancer-related surgery and pretreated with chemotherapy might benefit the most. |
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| 700 | 1 | _ | |a Schmidt, Martina |0 P:(DE-He78)2def8f8594c8f797f5ed4398258c6cac |b 1 |u dkfz |
| 700 | 1 | _ | |a Klassen, O. |0 P:(DE-HGF)0 |b 2 |
| 700 | 1 | _ | |a Debus, J. |b 3 |
| 700 | 1 | _ | |a Ulrich, C. M. |b 4 |
| 700 | 1 | _ | |a Potthoff, K. |b 5 |
| 700 | 1 | _ | |a Steindorf, Karen |0 P:(DE-He78)a0c2037d9054be26907a05ae520d5756 |b 6 |e Last author |u dkfz |
| 773 | _ | _ | |a 10.1111/sms.12777 |g Vol. 27, no. 11, p. 1500 - 1510 |0 PERI:(DE-600)2025503-2 |n 11 |p 1500 - 1510 |t Scandinavian journal of medicine & science in sports |v 27 |y 2017 |x 0905-7188 |
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