% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Zhan:131003,
      author       = {T. Zhan$^*$ and T. Hielscher$^*$ and F. Hahn and C. Hauf
                      and J. Betge$^*$ and M. P. Ebert and S. Belle},
      title        = {{R}isk {F}actors for {L}ocal {R}ecurrence of {L}arge,
                      {F}lat {C}olorectal {P}olyps after {E}ndoscopic {M}ucosal
                      {R}esection.},
      journal      = {Digestion},
      volume       = {93},
      number       = {4},
      issn         = {1421-9867},
      address      = {Basel},
      publisher    = {Karger},
      reportid     = {DKFZ-2017-06079},
      pages        = {311 - 317},
      year         = {2016},
      abstract     = {Removal of large, flat colorectal polyps by endoscopic
                      mucosal resection (EMR) is effective, but local recurrences
                      occur regularly. This study investigated risk factors for
                      local recurrence.Cases of EMR of flat colorectal polyps
                      ≥20 mm at an academic center from 2004 to 2011 were
                      retrospectively analyzed for polyp features, resection
                      technique, complications and local recurrences. Behavioral
                      risk factors were retrospectively determined by
                      self-administered questionnaires.Data were collected for 129
                      patients $(57.3\%$ male, mean age at time of EMR: 65.0
                      years). Mean polyp size was 37.2 mm. Polyps were mostly
                      adenoma with low-grade dysplasia $(58.1\%)$ and
                      predominantly located in the right colon $(62\%).$ En bloc
                      resection was performed in $31.8\%.$ The median follow-up
                      time was 40 months. Local recurrence occurred in $26.3\%$ of
                      patients, with $87\%$ being recurrence-free after 1 year
                      $(95\%$ CI $81-93\%).$ A history of smoking was reported by
                      $51.6\%$ of patients and $88.4\%$ reported regular alcohol
                      consumption. Univariate analysis showed that polyp size and
                      piecemeal resection were associated with risk of local
                      recurrence. In multivariate analysis, only polyp size was
                      predictive for local recurrence. No association was found
                      for behavioral risk factors.Polyp size is the main predictor
                      of local recurrence after EMR of large, flat colorectal
                      polyps.},
      cin          = {B110 / C060},
      ddc          = {610},
      cid          = {I:(DE-He78)B110-20160331 / I:(DE-He78)C060-20160331},
      pnm          = {312 - Functional and structural genomics (POF3-312)},
      pid          = {G:(DE-HGF)POF3-312},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:27271329},
      doi          = {10.1159/000446364},
      url          = {https://inrepo02.dkfz.de/record/131003},
}