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@ARTICLE{ZamoraRos:131743,
      author       = {R. Zamora-Ros and V. Béraud and S. Franceschi and V.
                      Cayssials and K. K. Tsilidis and M.-C. Boutron-Ruault and E.
                      Weiderpass and K. Overvad and A. Tjønneland and A. K.
                      Eriksen and F. Bonnet and A. Affret and V. Katzke$^*$ and T.
                      Kühn$^*$ and H. Boeing and A. Trichopoulou and E. Valanou
                      and A. Karakatsani and G. Masala and S. Grioni and M.
                      Santucci de Magistris and R. Tumino and F. Ricceri and G.
                      Skeie and C. L. Parr and S. Merino and E.
                      Salamanca-Fernández and M.-D. Chirlaque and E. Ardanaz and
                      P. Amiano and M. Almquist and I. Drake and J. Hennings and
                      M. Sandström and H. B. A. Bueno-de-Mesquita and P. H.
                      Peeters and K.-T. Khaw and N. J. Wareham and J. A. Schmidt
                      and A. Perez-Cornago and D. Aune and E. Riboli and N.
                      Slimani and A. Scalbert and I. Romieu and A. Agudo and S.
                      Rinaldi},
      title        = {{C}onsumption of fruits, vegetables and fruit juices and
                      differentiated thyroid carcinoma risk in the {E}uropean
                      {P}rospective {I}nvestigation into {C}ancer and {N}utrition
                      ({EPIC}) study.},
      journal      = {International journal of cancer},
      volume       = {142},
      number       = {3},
      issn         = {0020-7136},
      address      = {Bognor Regis},
      publisher    = {Wiley-Liss},
      reportid     = {DKFZ-2018-00049},
      pages        = {449 - 459},
      year         = {2018},
      abstract     = {Fruit and vegetable $(F\&V)$ intake is considered as
                      probably protective against overall cancer risk, but results
                      in previous studies are not consistent for thyroid cancer
                      (TC). The purpose of this study is to examine the
                      association between the consumption of fruits, vegetables,
                      fruit juices and differentiated thyroid cancer risk within
                      the European Prospective Investigation into Cancer and
                      Nutrition (EPIC) study. The EPIC study is a cohort including
                      over half a million participants, recruited between 1991 and
                      2000. During a mean follow-up of 14 years, 748 incident
                      first primary differentiated TC cases were identified.
                      $F\&V$ and fruit juice intakes were assessed through
                      validated country-specific dietary questionnaires. Hazard
                      ratios (HRs) and $95\%$ confidence intervals (CIs) were
                      estimated using Cox regression models adjusted for potential
                      confounding factors. Comparing the highest versus lowest
                      quartile of intake, differentiated TC risk was not
                      associated with intakes of total $F\&V$ (HR: 0.89; $95\%$
                      CI: 0.68-1.15; p-trend = 0.44), vegetables (HR: 0.89;
                      $95\%$ CI: 0.69-1.14; p-trend = 0.56), or fruit (HR:
                      1.00; $95\%$ CI: 0.79-1.26; p-trend = 0.64). No
                      significant association was observed with any individual
                      type of vegetable or fruit. However, there was a positive
                      borderline trend with fruit juice intake (HR: 1.23; $95\%$
                      CI: 0.98-1.53; p-trend = 0.06). This study did not find
                      any significant association between $F\&V$ intakes and
                      differentiated TC risk; however a positive trend with fruit
                      juice intake was observed, possibly related to its high
                      sugar content.},
      cin          = {C020},
      ddc          = {610},
      cid          = {I:(DE-He78)C020-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:28688112},
      doi          = {10.1002/ijc.30880},
      url          = {https://inrepo02.dkfz.de/record/131743},
}