TY  - JOUR
AU  - Barrdahl, Myrto
AU  - Canzian, Federico
AU  - Gaudet, Mia M
AU  - Gapstur, Susan M
AU  - Trichopoulou, Antonia
AU  - Tsilidis, Kostas
AU  - van Gils, Carla H
AU  - Borgquist, Signe
AU  - Weiderpass, Elisabete
AU  - Khaw, Kay-Tee
AU  - Giles, Graham G
AU  - Milne, Roger L
AU  - Le Marchand, Loic
AU  - Haiman, Christopher
AU  - Lindström, Sara
AU  - Kraft, Peter
AU  - Hunter, David J
AU  - Ziegler, Regina
AU  - Chanock, Stephen J
AU  - Yang, Xiaohong R
AU  - Buring, Julie E
AU  - Lee, I-Min
AU  - Kaaks, Rudolf
AU  - Campa, Daniele
TI  - A comprehensive analysis of polymorphic variants in steroid hormone and insulin-like growth factor-1 metabolism and risk of in situ breast cancer: Results from the Breast and Prostate Cancer Cohort Consortium.
JO  - International journal of cancer
VL  - 142
IS  - 6
SN  - 0020-7136
CY  - Bognor Regis
PB  - Wiley-Liss
M1  - DKFZ-2018-00063
SP  - 1182 - 1188
PY  - 2018
AB  - We assessed the association between 1,414 single nucleotide polymorphisms (SNPs) in genes involved in synthesis and metabolism of steroid hormones and insulin-like growth factor 1, and risk of breast cancer in situ (BCIS), with the aim of determining whether any of these were disease specific. This was carried out using 1,062 BCIS cases and 10,126 controls as well as 6,113 invasive breast cancer cases from the Breast and Prostate Cancer Cohort Consortium (BPC3). Three SNPs showed at least one nominally significant association in homozygous minor versus homozygous major models. ACVR2A-rs2382112 (ORhom  = 3.05, 95
LB  - PUB:(DE-HGF)16
C6  - pmid:29114882
DO  - DOI:10.1002/ijc.31145
UR  - https://inrepo02.dkfz.de/record/131766
ER  -