000132453 001__ 132453
000132453 005__ 20240229105017.0
000132453 0247_ $$2doi$$a10.1093/ecco-jcc/jjx136
000132453 0247_ $$2pmid$$apmid:29373726
000132453 0247_ $$2ISSN$$a1873-9946
000132453 0247_ $$2ISSN$$a1876-4479
000132453 037__ $$aDKFZ-2018-00141
000132453 041__ $$aeng
000132453 082__ $$a610
000132453 1001_ $$aAndersen, Vibeke$$b0
000132453 245__ $$aFibre intake and the development of inflammatory bowel disease: A European prospective multi-centre cohort study (EPIC-IBD).
000132453 260__ $$aOxford$$bOxford Univ. Press$$c2018
000132453 3367_ $$2DRIVER$$aarticle
000132453 3367_ $$2DataCite$$aOutput Types/Journal article
000132453 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1521446439_11799
000132453 3367_ $$2BibTeX$$aARTICLE
000132453 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000132453 3367_ $$00$$2EndNote$$aJournal Article
000132453 520__ $$aPopulation-based prospective cohort studies investigating fibre intake and development of inflammatory bowel disease are lacking. Our aim was to investigate the association between fibre intake and the development of Crohn's disease [CD] and ulcerative colitis [UC] in a large European population.In total, 401326 participants, aged 20-80 years, were recruited in eight countries in Europe between 1991 and 1998. At baseline, fibre intake [total fibres, fibres from fruit, vegetables and cereals] was recorded using food frequency questionnaires. The cohort was monitored for the development of inflammatory bowel disease. Each case was matched with four controls and odds ratios [ORs] for the exposures were calculated using conditional logistic regression. Sensitivity analyses according to smoking status were computed.In total, 104 and 221 participants developed incident CD and UC, respectively. For both CD and UC, there were no statistically significant associations with either quartiles, or trends across quartiles, for total fibre or any of the individual sources. The associations were not affected by adjusting for smoking and energy intake. Stratification according to smoking status showed null findings apart from an inverse association with cereal fibre and CD in non-smokers [Quartile 4 vs 1 OR = 0.12, 95% confidence interval = 0.02-0.75, p = 0.023, OR trend across quartiles = 0.50, 95% confidence interval = 0.29-0.86, p = 0.017].The results do not support the hypothesis that dietary fibre is involved in the aetiology of UC, although future work should investigate whether there may be a protective effect of specific types of fibre according to smoking status in CD.
000132453 536__ $$0G:(DE-HGF)POF3-313$$a313 - Cancer risk factors and prevention (POF3-313)$$cPOF3-313$$fPOF III$$x0
000132453 588__ $$aDataset connected to CrossRef, PubMed,
000132453 7001_ $$aChan, Simon$$b1
000132453 7001_ $$aLuben, Robert$$b2
000132453 7001_ $$aKhaw, Kay-Tee$$b3
000132453 7001_ $$aOlsen, Anja$$b4
000132453 7001_ $$aTjonneland, Anne$$b5
000132453 7001_ $$0P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a$$aKaaks, R.$$b6$$udkfz
000132453 7001_ $$aGrip, Olof$$b7
000132453 7001_ $$aBergmann, M. M.$$b8
000132453 7001_ $$aBoeing, H.$$b9
000132453 7001_ $$aHultdin, Johan$$b10
000132453 7001_ $$aKarling, Pontus$$b11
000132453 7001_ $$aOvervad, Kim$$b12
000132453 7001_ $$aOldenburg, Bas$$b13
000132453 7001_ $$aOpstelten, Jorrit$$b14
000132453 7001_ $$aBoutron-Ruault, Marie-Christine$$b15
000132453 7001_ $$aCarbonnel, Franck$$b16
000132453 7001_ $$aRacine, Antoine$$b17
000132453 7001_ $$aKey, Timothy$$b18
000132453 7001_ $$aMasala, Giovanna$$b19
000132453 7001_ $$aPalli, Domenico$$b20
000132453 7001_ $$aTumino, R.$$b21
000132453 7001_ $$aTrichopoulou, A.$$b22
000132453 7001_ $$aRiboli, Elio$$b23
000132453 7001_ $$aHart, Andrew$$b24
000132453 773__ $$0PERI:(DE-600)2389631-0$$a10.1093/ecco-jcc/jjx136$$gVol. 12, no. 2, p. 129 - 136$$n2$$p129 - 136$$tJournal of Crohn's and Colitis$$v12$$x1876-4479$$y2018
000132453 909CO $$ooai:inrepo02.dkfz.de:132453$$pVDB
000132453 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a$$aDeutsches Krebsforschungszentrum$$b6$$kDKFZ
000132453 9131_ $$0G:(DE-HGF)POF3-313$$1G:(DE-HGF)POF3-310$$2G:(DE-HGF)POF3-300$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vCancer risk factors and prevention$$x0
000132453 9141_ $$y2018
000132453 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bJ CROHNS COLITIS : 2015
000132453 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS
000132453 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline
000132453 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database
000132453 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bThomson Reuters Master Journal List
000132453 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded
000132453 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection
000132453 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine
000132453 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bJ CROHNS COLITIS : 2015
000132453 9201_ $$0I:(DE-He78)C020-20160331$$kC020$$lEpidemiologie von Krebserkrankungen$$x0
000132453 980__ $$ajournal
000132453 980__ $$aVDB
000132453 980__ $$aI:(DE-He78)C020-20160331
000132453 980__ $$aUNRESTRICTED