TY  - JOUR
AU  - Dossus, Laure
AU  - Franceschi, Silvia
AU  - Biessy, Carine
AU  - Navionis, Anne-Sophie
AU  - Travis, Ruth C
AU  - Weiderpass, Elisabete
AU  - Scalbert, Augustin
AU  - Romieu, Isabelle
AU  - Tjønneland, Anne
AU  - Olsen, Anja
AU  - Overvad, Kim
AU  - Boutron-Ruault, Marie-Christine
AU  - Bonnet, Fabrice
AU  - Fournier, Agnès
AU  - Turzanski-Fortner, Renée
AU  - Kaaks, Rudolf
AU  - Aleksandrova, Krasimira
AU  - Trichopoulou, Antonia
AU  - La Vecchia, Carlo
AU  - Peppa, Eleni
AU  - Tumino, Rosario
AU  - Panico, Salvatore
AU  - Palli, Domenico
AU  - Agnoli, Claudia
AU  - Vineis, Paolo
AU  - Bueno-de-Mesquita, H B As
AU  - Peeters, Petra H
AU  - Skeie, Guri
AU  - Zamora-Ros, Raul
AU  - Chirlaque, María-Dolores
AU  - Ardanaz, Eva
AU  - Sánchez, Maria-Jose
AU  - Ramón Quirós, Jose
AU  - Dorronsoro, Miren
AU  - Sandström, Maria
AU  - Nilsson, Lena Maria
AU  - Schmidt, Julie A
AU  - Khaw, Kay-Tee
AU  - Tsilidis, Konstantinos K
AU  - Aune, Dagfinn
AU  - Riboli, Elio
AU  - Rinaldi, Sabina
TI  - Adipokines and inflammation markers and risk of differentiated thyroid carcinoma: The EPIC study.
JO  - International journal of cancer
VL  - 142
IS  - 7
SN  - 0020-7136
CY  - Bognor Regis
PB  - Wiley-Liss
M1  - DKFZ-2018-00154
SP  - 1332 - 1342
PY  - 2018
AB  - Other than the influence of ionizing radiation and benign thyroid disease, little is known about the risk factors for differentiated thyroid cancer (TC) which is an increasing common cancer worldwide. Consistent evidence shows that body mass is positively associated with TC risk. As excess weight is a state of chronic inflammation, we investigated the relationship between concentrations of leptin, adiponectin, C-reactive protein, interleukin (IL)-6, IL-10 and tumor necrosis factor (TNF)-α and the risk of TC. A case-control study was nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) study and included 475 first primary incident TC cases (399 women and 76 men) and 1,016 matched cancer-free cohort participants. Biomarkers were measured in serum samples using validated and highly sensitive commercially available immunoassays. Odds ratios (ORs) of TC by levels of each biomarker were estimated using conditional logistic regression models, adjusting for BMI and alcohol consumption. Adiponectin was inversely associated with TC risk among women (ORT3vs.T1 = 0.69, 95
LB  - PUB:(DE-HGF)16
C6  - pmid:29168186
DO  - DOI:10.1002/ijc.31172
UR  - https://inrepo02.dkfz.de/record/132466
ER  -