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@ARTICLE{Bansi:132547,
      author       = {J. Bansi and C. Koliamitra and W. Bloch and N. Joisten and
                      A. Schenk and M. Watson and J. Kool and D. Langdon and U.
                      Dalgas and J. Kesselring and P. Zimmer$^*$},
      title        = {{P}ersons with secondary progressive and relapsing
                      remitting multiple sclerosis reveal different responses of
                      tryptophan metabolism to acute endurance exercise and
                      training.},
      journal      = {Journal of neuroimmunology},
      volume       = {314},
      issn         = {0165-5728},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {DKFZ-2018-00225},
      pages        = {101 - 105},
      year         = {2018},
      abstract     = {Disturbances in Tryptophan metabolism play a crucial role
                      in multiple sclerosis (MS). Exercise is suspected to
                      counteract the progress of MS and its side effects. Current
                      research suggests alterations of Tryptophan metabolism in
                      healthy individuals in response to exercise. We investigated
                      the influence of acute aerobic exercise and training on
                      Tryptophan metabolism in 57 inpatients with relapsing
                      remitting ((RRMS) n=33) and secondary progressive ((SPMS)
                      n=24) MS. Serotonin increased after training, whereas the
                      kynurenine pathway was only activated in persons with RRMS.
                      Further research is warranted to investigate whether these
                      changes are associated with clinical measures (e.g.
                      depressions and immune function).},
      cin          = {G210},
      ddc          = {610},
      cid          = {I:(DE-He78)G210-20160331},
      pnm          = {317 - Translational cancer research (POF3-317)},
      pid          = {G:(DE-HGF)POF3-317},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29224960},
      doi          = {10.1016/j.jneuroim.2017.12.001},
      url          = {https://inrepo02.dkfz.de/record/132547},
}