TY  - JOUR
AU  - Büchele, G.
AU  - Günther, K. P.
AU  - Brenner, H.
AU  - Puhl, W.
AU  - Stürmer, T.
AU  - Rothenbacher, D.
AU  - Brenner, R. E.
TI  - Osteoarthritis-patterns, cardio-metabolic risk factors and risk of all-cause mortality: 20 years follow-up in patients after hip or knee replacement.
JO  - Scientific reports
VL  - 8
IS  - 1
SN  - 2045-2322
CY  - London
PB  - Nature Publishing Group
M1  - DKFZ-2018-00352
SP  - 5253
PY  - 2018
AB  - Osteoarthritis (OA) is a common musculoskeletal disorder and occur in different patterns. However, its impact on long-term all-cause-mortality is inconclusive.Investigate 20-year all-cause-mortality in patients with hip/knee arthroplasty (recruited 1995/1996, N = 809) from the Ulm Osteoarthritis Study-cohort, in comparison to general population. Furthermore, to enlighten the triangle between baseline life-style and cardio-metabolic risk factors, phenotypic OA-patterns (laterality, generalization, cause) and all-cause-mortality. Mortality was assessed during 20 years follow-up. Standardized mortality ratios (SMR), adjusted odds ratios and hazard ratios (aHR) were calculated. After five years cohort-mortality was reduced compared to the general population, however 20 years later assimilated (SMR = 1.11; 95
LB  - PUB:(DE-HGF)16
C6  - pmid:29588472
C2  - pmc:PMC5869736
DO  - DOI:10.1038/s41598-018-23573-2
UR  - https://inrepo02.dkfz.de/record/132695
ER  -