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@ARTICLE{Erben:132710,
author = {V. Erben$^*$ and P. Carr$^*$ and B. Holleczek and C.
Stegmaier and M. Hoffmeister$^*$ and H. Brenner$^*$},
title = {{D}ietary patterns and risk of advanced colorectal
neoplasms: {A} large population based screening study in
{G}ermany.},
journal = {Preventive medicine},
volume = {111},
issn = {0091-7435},
address = {Amsterdam},
publisher = {Elsevier},
reportid = {DKFZ-2018-00364},
pages = {101 - 109},
year = {2018},
abstract = {Specific components of the diet such as red and processed
meat have been associated with the risk of developing
colorectal cancer. However, evidence on the association of
dietary patterns with colorectal neoplasms is sparse. The
aim of this study was to analyze the association of dietary
patterns with prevalence of advanced colorectal neoplasms
among older adults in Germany. A cross-sectional study was
conducted among participants of screening colonoscopy in
Saarland, Germany, who were enrolled in the KolosSal study
(Effektivität der Früherkennungs-Koloskopie: eine
Saarland-weite Studie) from 2005 to 2013. Information on
diet and lifestyle factors was obtained through
questionnaires and colonoscopy results were extracted from
physicians' reports. Associations of a priori defined
dietary patterns (vegetarian or adapted versions of the
Healthy Eating Index [HEI] and the Dietary Approaches to
Stop Hypertension [DASH] index) with the risk of advanced
colorectal neoplasms were assessed by multiple logistic
regression analyses with comprehensive adjustment for
potential confounders. A total of 14,309 participants were
included (1561 with advanced colorectal neoplasms).
Healthier eating behavior was associated with lower
prevalence of advanced colorectal neoplasms in a
dose-response manner. Adjusted odds ratios $(95\%$
confidence intervals) comparing the highest with the lowest
categories of adapted HEI and DASH were 0.61 (0.50, 0.76)
and 0.70 (0.55, 0.89), respectively. No significant
associations were observed for a vegetarian eating pattern
(adjusted OR 0.80 (0.55, 1.17)). Healthy dietary patterns,
as described by a high HEI or DASH score, but not a
vegetarian diet alone, are associated with reduced risk of
advanced colorectal neoplasms.},
cin = {C070 / G110 / L101},
ddc = {610},
cid = {I:(DE-He78)C070-20160331 / I:(DE-He78)G110-20160331 /
I:(DE-He78)L101-20160331},
pnm = {313 - Cancer risk factors and prevention (POF3-313)},
pid = {G:(DE-HGF)POF3-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:29477967},
doi = {10.1016/j.ypmed.2018.02.025},
url = {https://inrepo02.dkfz.de/record/132710},
}