000132748 001__ 132748
000132748 005__ 20240229105030.0
000132748 0247_ $$2doi$$a10.1093/ibd/izx050
000132748 0247_ $$2pmid$$apmid:29462382
000132748 0247_ $$2ISSN$$a1078-0998
000132748 0247_ $$2ISSN$$a1536-4844
000132748 0247_ $$2altmetric$$aaltmetric:33473104
000132748 037__ $$aDKFZ-2018-00401
000132748 041__ $$aeng
000132748 082__ $$a610
000132748 1001_ $$aOpstelten, Jorrit L$$b0
000132748 245__ $$aPrediagnostic Serum Vitamin D Levels and the Risk of Crohn's Disease and Ulcerative Colitis in European Populations: A Nested Case-Control Study.
000132748 260__ $$aPhiladelphia, Pa.$$bLippincott Williams & Wilkins$$c2018
000132748 3367_ $$2DRIVER$$aarticle
000132748 3367_ $$2DataCite$$aOutput Types/Journal article
000132748 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1524827897_15060
000132748 3367_ $$2BibTeX$$aARTICLE
000132748 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000132748 3367_ $$00$$2EndNote$$aJournal Article
000132748 520__ $$aA low vitamin D status has been put forward as a potential risk factor for the development of inflammatory bowel disease (IBD). This study investigated the association between prediagnostic circulating vitamin D concentrations and dietary intakes of vitamin D, and the risk of Crohn's disease (CD) and ulcerative colitis (UC).Among 359,728 participants of the European Prospective Investigation into Cancer and Nutrition cohort, individuals who developed CD or UC after enrollment were identified. Each case was matched with2 controls by center, gender, age, date of recruitment, and follow-up time. At cohort entry, blood samples were collected and dietary vitamin D intakes were obtained from validated food frequency questionnaires. Serum 25-hydroxyvitamin D levels were measured using liquid chromatography-tandem mass spectrometry. Conditional logistic regression was performed to determine the odds of CD and UC.Seventy-two participants developed CD and 169 participants developed UC after a median follow-up of 4.7 and 4.1 years, respectively. Compared with the lowest quartile, no associations with the 3 higher quartiles of vitamin D concentrations were observed for CD (p trend = 0.34) or UC (p trend = 0.66). Similarly, no associations were detected when serum vitamin D levels were analyzed as a continuous variable. Dietary vitamin D intakes were not associated with CD (p trend = 0.39) or UC (p trend = 0.83).Vitamin D status was not associated with the development of CD or UC. This does not suggest a major role for vitamin D deficiency in the etiology of IBD, although larger studies are needed to confirm these findings.
000132748 536__ $$0G:(DE-HGF)POF3-313$$a313 - Cancer risk factors and prevention (POF3-313)$$cPOF3-313$$fPOF III$$x0
000132748 588__ $$aDataset connected to CrossRef, PubMed,
000132748 7001_ $$aChan, Simon S M$$b1
000132748 7001_ $$aHart, Andrew R$$b2
000132748 7001_ $$avan Schaik, Fiona D M$$b3
000132748 7001_ $$aSiersema, Peter D$$b4
000132748 7001_ $$aLentjes, Eef G W M$$b5
000132748 7001_ $$aKhaw, Kay-Tee$$b6
000132748 7001_ $$aLuben, Robert$$b7
000132748 7001_ $$aKey, Timothy J$$b8
000132748 7001_ $$aBoeing, Heiner$$b9
000132748 7001_ $$aBergmann, Manuela M$$b10
000132748 7001_ $$aOvervad, Kim$$b11
000132748 7001_ $$aPalli, Domenico$$b12
000132748 7001_ $$aMasala, Giovanna$$b13
000132748 7001_ $$aRacine, Antoine$$b14
000132748 7001_ $$aCarbonnel, Franck$$b15
000132748 7001_ $$aBoutron-Ruault, Marie-Christine$$b16
000132748 7001_ $$aTjønneland, Anne$$b17
000132748 7001_ $$aOlsen, Anja$$b18
000132748 7001_ $$aAndersen, Vibeke$$b19
000132748 7001_ $$0P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a$$aKaaks, Rudolf$$b20$$udkfz
000132748 7001_ $$0P:(DE-He78)0907a10ba1dc8f53f04907f54f6fdcfe$$aKühn, Tilman$$b21$$udkfz
000132748 7001_ $$aTumino, Rosario$$b22
000132748 7001_ $$aTrichopoulou, Antonia$$b23
000132748 7001_ $$aPeeters, Petra H M$$b24
000132748 7001_ $$aVerschuren, W M Monique$$b25
000132748 7001_ $$aWitteman, Ben J M$$b26
000132748 7001_ $$aOldenburg, Bas$$b27
000132748 773__ $$0PERI:(DE-600)2065065-6$$a10.1093/ibd/izx050$$gVol. 24, no. 3, p. 633 - 640$$n3$$p633 - 640$$tInflammatory bowel diseases$$v24$$x1536-4844$$y2018
000132748 909CO $$ooai:inrepo02.dkfz.de:132748$$pVDB
000132748 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a$$aDeutsches Krebsforschungszentrum$$b20$$kDKFZ
000132748 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)0907a10ba1dc8f53f04907f54f6fdcfe$$aDeutsches Krebsforschungszentrum$$b21$$kDKFZ
000132748 9131_ $$0G:(DE-HGF)POF3-313$$1G:(DE-HGF)POF3-310$$2G:(DE-HGF)POF3-300$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vCancer risk factors and prevention$$x0
000132748 9141_ $$y2018
000132748 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline
000132748 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database
000132748 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bINFLAMM BOWEL DIS : 2015
000132748 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS
000132748 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bThomson Reuters Master Journal List
000132748 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index
000132748 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection
000132748 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded
000132748 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine
000132748 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5
000132748 9201_ $$0I:(DE-He78)C020-20160331$$kC020$$lEpidemiologie von Krebserkrankungen$$x0
000132748 980__ $$ajournal
000132748 980__ $$aVDB
000132748 980__ $$aI:(DE-He78)C020-20160331
000132748 980__ $$aUNRESTRICTED