TY  - JOUR
AU  - Wild, Esther
AU  - Teber, Dogu
AU  - Schmid, Daniel
AU  - Simpfendörfer, Tobias
AU  - Müller, Michael
AU  - Baranski, Ann-Christin
AU  - Kenngott, Hannes
AU  - Kopka, Klaus
AU  - Maier-Hein, Lena
TI  - Robust augmented reality guidance with fluorescent markers in laparoscopic surgery.
JO  - International journal of computer assisted radiology and surgery
VL  - 11
IS  - 6
SN  - 1861-6429
CY  - Berlin
PB  - Springer
M1  - DKFZ-2018-00486
SP  - 899 - 907
PY  - 2016
AB  - Laparoscopic interventions require the precise navigation of medical instruments through the patient's body, while taking critical structures into account. Although numerous concepts have been proposed for displaying subsurface anatomical detail using augmented reality, clinical translation of these methods has suffered from a lack of robustness as well as from cumbersome integration into the clinical workflow. The purpose of this study was to investigate the feasibility of a new approach to intra-operative registration based on fluorescent markers.The proposed approach to augmented reality visualization relies on metabolizable fluorescent markers that are attached to the target organ to guide a 2D/3D intra-operative registration algorithm. In an ex vivo porcine study, marker tracking performance is evaluated in the presence of smoke, blood, and tissue in the field of view of the endoscope.In contrast to state-of-the-art needle-shaped fiducial markers, the fluorescent markers can be reliably tracked when occluded by smoke, blood or tissue. This makes the new 2D/3D intra-operative registration approach considerably more robust than state-of-the-art marker-based methods.As the concept can be smoothly integrated into the clinical workflow, its potential for application in clinical laparoscopy is high.
KW  - Coloring Agents (NLM Chemicals)
KW  - Indocyanine Green (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:27177759
DO  - DOI:10.1007/s11548-016-1385-4
UR  - https://inrepo02.dkfz.de/record/132843
ER  -