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@ARTICLE{Rogers:132854,
author = {S. Rogers and D. Jones$^*$ and A. Ireland and N. G.
Gottardo and R. Endersby},
title = {{U}nusual paediatric spinal myxopapillary ependymomas:
{U}nique molecular entities or pathological variations on a
theme?},
journal = {Journal of clinical neuroscience},
volume = {50},
issn = {0967-5868},
address = {Burlington, Mass.},
publisher = {Harcourt},
reportid = {DKFZ-2018-00497},
pages = {144 - 148},
year = {2018},
abstract = {Ependymomas are the commonest type of spinal glioma which
represent a group of relatively benign tumours.
Myxopapillary ependymoma (MPE) is a common variant found
within the distal spinal cord around the conus. These two
entities are clearly differentiated on the basis of their
characteristic histological and molecular features. Rare
variants of MPE's are described in the literature to have
the propensity to metastasise and grow in extraspinal
locations despite appearing histologically identical to
their more benign relatives. Here, we describe two unusual
cases of MPE and utilise DNA methylation analyses to compare
their molecular signatures with known molecular subtypes of
ependymoma in an attempt to distinguish whether these
tumours represent a unique subset of disease.},
cin = {B062},
ddc = {610},
cid = {I:(DE-He78)B062-20160331},
pnm = {312 - Functional and structural genomics (POF3-312)},
pid = {G:(DE-HGF)POF3-312},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:29402569},
doi = {10.1016/j.jocn.2018.01.048},
url = {https://inrepo02.dkfz.de/record/132854},
}