TY  - JOUR
AU  - Gigic, Biljana
AU  - Boeing, Heiner
AU  - Toth, Reka
AU  - Böhm, Jürgen
AU  - Habermann, Nina
AU  - Scherer, Dominique
AU  - Schrotz-King, Petra
AU  - Abbenhardt-Martin, Clare
AU  - Skender, Stephanie
AU  - Brenner, Hermann
AU  - Chang-Claude, Jenny
AU  - Hoffmeister, Michael
AU  - Syrjala, Karen
AU  - Jacobsen, Paul B
AU  - Schneider, Martin
AU  - Ulrich, Alexis
AU  - Ulrich, Cornelia M
TI  - Associations Between Dietary Patterns and Longitudinal Quality of Life Changes in Colorectal Cancer Patients: The ColoCare Study.
JO  - Nutrition and cancer
VL  - 70
IS  - 1
SN  - 1532-7914
CY  - New York, NY
PB  - Routledge, Taylor & Francis Group
M1  - DKFZ-2018-00528
SP  - 51 - 60
PY  - 2018
AB  - Quality of life (QoL) is an important clinical outcome in cancer patients. We investigated associations between dietary patterns and QoL changes in colorectal cancer (CRC) patients. The study included 192 CRC patients with available EORTC QLQ-C30 data before and 12 months post-surgery and food frequency questionnaire data at 12 months post-surgery. Principal component analysis was used to identify dietary patterns. Multivariate regression models assessed associations between dietary patterns and QoL changes over time. We identified four major dietary patterns: 'Western' dietary pattern characterized by high consumption of potatoes, red and processed meat, poultry, and cakes, 'fruit</td><td width="150">
AB  - vegetable' pattern: high intake of vegetables, fruits, vegetable oils, and soy products, 'bread</td><td width="150">
AB  - butter' pattern: high intake of bread, butter and margarine, and 'high-carb' pattern: high consumption of pasta, grains, nonalcoholic beverages, sauces and condiments. Patients following a 'Western' diet had lower chances to improve in physical functioning (OR = 0.45 [0.21-0.99]), constipation (OR = 0.30 [0.13-0.72]) and diarrhea (OR: 0.44 [0.20-0.98]) over time. Patients following a 'fruit</td><td width="150">
AB  - vegetable' diet showed improving diarrhea scores (OR: 2.52 [1.21-5.34]. A 'Western' dietary pattern after surgery is inversely associated with QoL in CRC patients, whereas a diet rich in fruits and vegetables may be beneficial for patients' QoL over time.
LB  - PUB:(DE-HGF)16
C6  - pmid:29244538
C2  - pmc:PMC5867188
DO  - DOI:10.1080/01635581.2018.1397707
UR  - https://inrepo02.dkfz.de/record/132886
ER  -