%0 Journal Article
%A Mattke, Matthias
%A Vogt, Kira
%A Bougatf, Nina
%A Welzel, Thomas
%A Oelmann-Avendano, Jan
%A Hauswald, Henrik
%A Jensen, Alexandra
%A Ellerbrock, Malte
%A Jäkel, Oliver
%A Haberer, Thomas
%A Herfarth, Klaus
%A Debus, Jürgen
%A Uhl, Matthias
%T High control rates of proton- and carbon-ion-beam treatment with intensity-modulated active raster scanning in 101 patients with skull base chondrosarcoma at the Heidelberg Ion Beam Therapy Center.
%J Cancer cytopathology
%V 124
%N 9
%@ 0008-543X
%C Hoboken, NJ
%I Wiley48362
%M DKFZ-2018-00534
%P 2036 - 2044
%D 2018
%X The current study compares the results of irradiation with protons and irradiation with carbon ions via a raster scan technique in patients with G1 and G2 skull base chondrosarcomas.Between 2009 and 2014, a total of 101 patients (40 men and 61 women) with a median age of 44 years (range, 19-77 years) were irradiated with carbon ions (79 patients) or protons (22 patients) via a raster scan technique at the Heidelberg Ion Beam Therapy Center. The median total dose was 60 Gy (relative biological effectiveness [RBE]) at 3 Gy per fraction for carbon ions and 70 Gy (RBE) at 2 Gy per fraction for protons. The median boost planning target volume was 38 cm3 (range, 8-133 cm3 ). Overall survival (OS) and local control (LC) were evaluated with the Kaplan-Meier method.The median follow-up period was 40 months (range, 0.8-78.1 months). At the start of the irradiation, all patients had residual macroscopic tumors. Five patients (5
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:29469932
%R 10.1002/cncr.31298
%U https://inrepo02.dkfz.de/record/132892