TY  - JOUR
AU  - Mattke, Matthias
AU  - Vogt, Kira
AU  - Bougatf, Nina
AU  - Welzel, Thomas
AU  - Oelmann-Avendano, Jan
AU  - Hauswald, Henrik
AU  - Jensen, Alexandra
AU  - Ellerbrock, Malte
AU  - Jäkel, Oliver
AU  - Haberer, Thomas
AU  - Herfarth, Klaus
AU  - Debus, Jürgen
AU  - Uhl, Matthias
TI  - High control rates of proton- and carbon-ion-beam treatment with intensity-modulated active raster scanning in 101 patients with skull base chondrosarcoma at the Heidelberg Ion Beam Therapy Center.
JO  - Cancer cytopathology
VL  - 124
IS  - 9
SN  - 0008-543X
CY  - Hoboken, NJ
PB  - Wiley48362
M1  - DKFZ-2018-00534
SP  - 2036 - 2044
PY  - 2018
AB  - The current study compares the results of irradiation with protons and irradiation with carbon ions via a raster scan technique in patients with G1 and G2 skull base chondrosarcomas.Between 2009 and 2014, a total of 101 patients (40 men and 61 women) with a median age of 44 years (range, 19-77 years) were irradiated with carbon ions (79 patients) or protons (22 patients) via a raster scan technique at the Heidelberg Ion Beam Therapy Center. The median total dose was 60 Gy (relative biological effectiveness [RBE]) at 3 Gy per fraction for carbon ions and 70 Gy (RBE) at 2 Gy per fraction for protons. The median boost planning target volume was 38 cm3 (range, 8-133 cm3 ). Overall survival (OS) and local control (LC) were evaluated with the Kaplan-Meier method.The median follow-up period was 40 months (range, 0.8-78.1 months). At the start of the irradiation, all patients had residual macroscopic tumors. Five patients (5
LB  - PUB:(DE-HGF)16
C6  - pmid:29469932
DO  - DOI:10.1002/cncr.31298
UR  - https://inrepo02.dkfz.de/record/132892
ER  -