%0 Journal Article
%A Afshar-Oromieh, Ali
%A Sattler, Lars Peter
%A Steiger, Katja
%A Holland-Letz, Tim
%A da Cunha, Marcelo Livorsi
%A Mier, Walter
%A Neels, Oliver
%A Kopka, Klaus
%A Weichert, Wilko
%A Haberkorn, Uwe
%T Tracer uptake in mediastinal and paraaortal thoracic lymph nodes as a potential pitfall in image interpretation of PSMA ligand PET/CT.
%J European journal of nuclear medicine and molecular imaging
%V 45
%N 7
%@ 1619-7089
%C Heidelberg [u.a.]
%I Springer-Verl.
%M DKFZ-2018-00592
%P 1179 - 1187
%D 2018
%X Since the introduction of 68Ga-PSMA-11 PET/CT for imaging prostate cancer (PC) we have frequently observed mediastinal lymph nodes (LN) showing tracer uptake despite being classified as benign. The aim of this evaluation was to further analyze such LN.Two patient groups with biphasic 68Ga-PSMA-11 PET/CT at 1 h and 3 h p.i. were included in this retrospective evaluation. Group A (n = 38) included patients without LN metastases, and group B (n = 43) patients with LN metastases of PC. SUV of mediastinal/paraaortal LN of group A (n = 100) were compared to SUV of LN metastases of group B (n = 91). Additionally, 22 randomly selected mediastinal and paraaortal LN of patients without PC were immunohistochemically (IHC) analyzed for PSMA expression.In group A, 7/38 patients (18.4
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:29497802
%R 10.1007/s00259-018-3965-8
%U https://inrepo02.dkfz.de/record/134799