TY  - JOUR
AU  - Wunram, Heidrun Lioba
AU  - Hamacher, Stefanie
AU  - Hellmich, Martin
AU  - Volk, Maxi
AU  - Jänicke, Franziska
AU  - Reinhard, Franziska
AU  - Bloch, Wilhelm
AU  - Zimmer, Philipp
AU  - Graf, Christine
AU  - Schönau, Eckhard
AU  - Lehmkuhl, Gerd
AU  - Bender, Stephan
AU  - Fricke, Oliver
TI  - Whole body vibration added to treatment as usual is effective in adolescents with depression: a partly randomized, three-armed clinical trial in inpatients.
JO  - European child & adolescent psychiatry
VL  - 27
IS  - 5
SN  - 1018-8827
CY  - Darmstadt
PB  - Steinkopff
M1  - DKFZ-2018-00634
SP  - 645 - 662
PY  - 2018
AB  - There is growing evidence for the effectiveness of exercise in the treatment of adult major depression. With regard to adolescents, clinical trials are scarce. Due to the inherent symptoms of depression (lack of energy, low motivation to exercise), endurance training forms could be too demanding especially in the first weeks of treatment. We hypothesized that an easy-to-perform passive muscular training on a whole body vibration (WBV) device has equal anti-depressive effects compared to a cardiovascular training, both administered as add-ons to treatment as usual (TAU). Secondly, we presumed that both exercise interventions would be superior in their response, compared to TAU. In 2 years 64 medication-naïve depressed inpatients aged 13-18, were included. Both exercise groups fulfilled a supervised vigorous training for 6 weeks. Depressive symptoms were assessed by self-report ('Depressions Inventar für Kinder und Jugendliche'-DIKJ) before intervention and after weeks 6, 14 and 26. Compared to TAU, both groups responded earlier and more strongly measured by DIKJ scores, showing a trend for the WBV group after week 6 (p = 0.082). The decrease became statistically significant for both intervention groups after week 26 (p = 0.037 for ergometer and p = 0.042 for WBV). Remission rates amounted to 39.7
LB  - PUB:(DE-HGF)16
C6  - pmid:29119301
DO  - DOI:10.1007/s00787-017-1071-2
UR  - https://inrepo02.dkfz.de/record/134844
ER  -