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@ARTICLE{Majdinasab:134858,
author = {N. Majdinasab and R. W. Motl and M. Mokhtarzade and P.
Zimmer$^*$ and R. Ranjbar and C. Keytsman and T. Cullen and
R. Negaresh and J. S. Baker},
title = {{A}cute responses of cytokines and adipokines to aerobic
exercise in relapsing vs. remitting women with multiple
sclerosis.},
journal = {Complementary therapies in clinical practice},
volume = {31},
issn = {1744-3881},
address = {Edinburgh [u.a.]},
publisher = {Elsevier44913},
reportid = {DKFZ-2018-00648},
pages = {295 - 301},
year = {2018},
abstract = {To examine the acute effect of exercise on cytokines and
adipokines during relapse and the remitting phase of
multiple sclerosis (MS).Thirty women with MS in the
relapsing or remitting phase were matched with fifteen
healthy controls. Participants performed a single-bout of
aerobic exercise at $60-70\%$ maximal heart rate.
Furthermore, five women in the relapsing phase were enrolled
(control relapse) and did not receive any intervention.
Blood samples were taken before, immediately after, 1-h and
6-h after the exercise.Levels of IL-10 and TNF-α in
response to exercise were similar in healthy and MS
remitting subjects. Compared to baseline, TNF-α levels in
relapsing subjects were significantly decreased immediately
after exercise. Immediately following exercise, leptin
levels significantly decreased in relapsing subjects.
Adiponectin and IL-6 showed no significant difference
between groups.After relapse, exercise does not induce
inflammatory cytokine response and temporarily improves both
cytokine and adipokine balance.},
cin = {G210},
ddc = {610},
cid = {I:(DE-He78)G210-20160331},
pnm = {317 - Translational cancer research (POF3-317)},
pid = {G:(DE-HGF)POF3-317},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:29705471},
doi = {10.1016/j.ctcp.2018.03.004},
url = {https://inrepo02.dkfz.de/record/134858},
}