%0 Journal Article
%A Gies, Anton
%A Bhardwaj, Megha
%A Stock, Christian
%A Schrotz-King, Petra
%A Brenner, Hermann
%T Quantitative fecal immunochemical tests for colorectal cancer screening.
%J International journal of cancer
%V 143
%N 2
%@ 0020-7136
%C Bognor Regis
%I Wiley-Liss
%M DKFZ-2018-00692
%P 234 - 244
%D 2018
%X Fecal immunochemical tests (FITs) for hemoglobin (Hb) are increasingly used for colorectal cancer (CRC) screening. We aimed to review, summarize and compare reported diagnostic performance of various FITs. PubMed and Web of Science were searched from inception to July 24, 2017. Data on diagnostic performance of quantitative FITs, conducted in colonoscopy-controlled average-risk screening populations, were extracted. Summary receiver operating characteristic (ROC) curves were plotted and correlations between thresholds, positivity rates (PRs), sensitivities and specificities were assessed. Seven test brands were investigated across 22 studies. Although reported sensitivities for CRC, advanced adenoma (AA) and any advanced neoplasm (AN) varied widely (ranges: 25-100
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:29277897
%R 10.1002/ijc.31233
%U https://inrepo02.dkfz.de/record/135955