TY  - JOUR
AU  - Gies, Anton
AU  - Bhardwaj, Megha
AU  - Stock, Christian
AU  - Schrotz-King, Petra
AU  - Brenner, Hermann
TI  - Quantitative fecal immunochemical tests for colorectal cancer screening.
JO  - International journal of cancer
VL  - 143
IS  - 2
SN  - 0020-7136
CY  - Bognor Regis
PB  - Wiley-Liss
M1  - DKFZ-2018-00692
SP  - 234 - 244
PY  - 2018
AB  - Fecal immunochemical tests (FITs) for hemoglobin (Hb) are increasingly used for colorectal cancer (CRC) screening. We aimed to review, summarize and compare reported diagnostic performance of various FITs. PubMed and Web of Science were searched from inception to July 24, 2017. Data on diagnostic performance of quantitative FITs, conducted in colonoscopy-controlled average-risk screening populations, were extracted. Summary receiver operating characteristic (ROC) curves were plotted and correlations between thresholds, positivity rates (PRs), sensitivities and specificities were assessed. Seven test brands were investigated across 22 studies. Although reported sensitivities for CRC, advanced adenoma (AA) and any advanced neoplasm (AN) varied widely (ranges: 25-100
LB  - PUB:(DE-HGF)16
C6  - pmid:29277897
DO  - DOI:10.1002/ijc.31233
UR  - https://inrepo02.dkfz.de/record/135955
ER  -