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@ARTICLE{Platt:135965,
      author       = {T. Platt$^*$ and R. Umathum$^*$ and T. Fiedler$^*$ and A.
                      Nagel$^*$ and A. Bitz$^*$ and F. Maier$^*$ and P.
                      Bachert$^*$ and M. Ladd$^*$ and M. O. Wielpütz and H.-U.
                      Kauczor and N. Behl$^*$},
      title        = {{I}n vivo self-gated 23 {N}a {MRI} at 7 {T} using an
                      oval-shaped body resonator.},
      journal      = {Magnetic resonance in medicine},
      volume       = {80},
      number       = {3},
      issn         = {0740-3194},
      address      = {New York, NY [u.a.]},
      publisher    = {Wiley-Liss},
      reportid     = {DKFZ-2018-00702},
      pages        = {1005 - 1019},
      year         = {2018},
      abstract     = {This work faces three challenges of sodium (23 Na) torso
                      MRI on the way to quantitative 23 Na MRI: Development of a
                      23 Na radiofrequency transmit and receive coil covering a
                      large part of the human body in width and length for 23 Na
                      MRI at 7 T; reduction of blurring due to respiration in
                      free-breathing 23 Na MRI using a self-gating approach; and
                      reduction of image noise using a compressed-sensing
                      reconstruction.An oval-shaped birdcage resonator with a
                      large field of view of (400 mm)3 and a homogeneous transmit
                      and receive field distribution was designed, simulated, and
                      implemented on a 7T MR system. In free-breathing
                      3-dimensional radial 23 Na MRI (acquisition time ≈ 30
                      minutes), retrospective respiratory self-gating was applied,
                      which sorts the acquired projections into two respiratory
                      states based on the intrinsic respiration-dependent signal
                      changes. Furthermore, a 3-dimensional dictionary-learning
                      compressed-sensing reconstruction was applied.The developed
                      body coil provided homogeneous radiofrequency excitation
                      (flip angle error of $4.9\%$ in central region of interest
                      of 23 × 13 × 10 cm3 ) and homogeneous signal
                      reception. The self-gating approach allowed for separation
                      of the full data set into two subsets associated with
                      different respiratory states (inhaled and exhaled), and
                      thereby reduced blurring due to respiration in the separated
                      images. Image noise was markedly reduced by the
                      compressed-sensing algorithm.The presented body coil enables
                      full body width 23 Na MRI with long z-axis coverage at 7 T
                      for the first time. Additionally, the retrospective
                      respiratory self-gating performance is demonstrated for
                      free-breathing lung and abdominal 23 Na MRI in 3 subjects.},
      cin          = {E020},
      ddc          = {610},
      cid          = {I:(DE-He78)E020-20160331},
      pnm          = {315 - Imaging and radiooncology (POF3-315)},
      pid          = {G:(DE-HGF)POF3-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29427389},
      doi          = {10.1002/mrm.27103},
      url          = {https://inrepo02.dkfz.de/record/135965},
}