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| Home > Publications database > Time trends in dyspepsia and association with H. pylori and work-related stress-An observational study in white collar employees in 1996 and 2015. > print |
| Home > Publications database > Time trends in dyspepsia and association with H. pylori and work-related stress-An observational study in white collar employees in 1996 and 2015. > print |
| 001 | 136665 | ||
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| 100 | 1 | _ | |a Braig, Stefanie |0 0000-0003-0757-5045 |b 0 |
| 245 | _ | _ | |a Time trends in dyspepsia and association with H. pylori and work-related stress-An observational study in white collar employees in 1996 and 2015. |
| 260 | _ | _ | |a Lawrence, Kan. |c 2018 |b PLoS |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 520 | _ | _ | |a We aimed to describe time trends in functional dyspepsia and the association of dyspepsia-related factors, Helicobacter pylori (H. pylori) and work-related stress with functional dyspepsia in white collar employees in 1996 and 2015.Repeat cross-sectional study conducted in 1996 (n = 190, response rate = 76.1) and 2015 (n = 195, response rate = 40.2) within a health insurance company in South-West Germany. Dyspeptic symptoms measured according to the Rome III criteria, effort-reward imbalance and further work- or dyspepsia-related factors were assessed by self-administered questionnaire. H. pylori infection as possible factor for dyspeptic symptoms was measured by a 13C-urea breath test or an antigen stool test. Kruskal-Wallis tests and multivariable logistic regression models were calculated comparing the upper tertile of dyspeptic symptom scale to the middle and lower tertile.Mean dyspepsia symptom scores and work-related stress did not differ comparing 1996 and 2015. In bivariate analyses, dyspeptic symptom scores were consistently correlated with sex, age, and using antacids. Further dyspepsia-related factors were smoking and non-leading occupational position in 1996 and non-steroidal anti-inflammatory drugs as well as high effort-reward imbalance in 2015. High intrinsic effort was positively associated with high dyspepsia symptom scores in both studies. Following multivariable adjustment, we observed a consistent association between high intrinsic effort at work and dyspeptic symptoms, although the association was only marginally statistically significant in 1996. Furthermore, a strong association of somatization, only measured in 2015, with dyspeptic symptoms was shown.Dyspepsia-related factors may have changed throughout the last decades. Nevertheless, although occupational situations might differ, the intrinsic effort is still strongly associated with dyspeptic symptoms. |
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| 700 | 1 | _ | |a Berger, Simon |b 1 |
| 700 | 1 | _ | |a Rothenbacher, David |b 2 |
| 700 | 1 | _ | |a Schmid, Stefanie |b 3 |
| 700 | 1 | _ | |a Seufferlein, Thomas |b 4 |
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| 700 | 1 | _ | |a Rothenbacher, Dietrich |b 6 |
| 700 | 1 | _ | |a Gündel, Harald |b 7 |
| 773 | _ | _ | |a 10.1371/journal.pone.0199533 |g Vol. 13, no. 6, p. e0199533 - |0 PERI:(DE-600)2267670-3 |n 6 |p e0199533 |t PLoS one |v 13 |y 2018 |x 1932-6203 |
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