TY  - JOUR
AU  - Huhn, Stefanie
AU  - da Silva Filho, Miguel I
AU  - Sanmuganantham, Tharmila
AU  - Pichulik, Tica
AU  - Catalano, Calogerina
AU  - Pardini, Barbara
AU  - Naccarati, Alessio
AU  - Polakova-Vymetálkova, Veronika
AU  - Jiraskova, Katerina
AU  - Vodickova, Ludmila
AU  - Vodicka, Pavel
AU  - Löffler, Markus W
AU  - Courth, Lioba
AU  - Wehkamp, Jan
AU  - Din, Farhat V N
AU  - Timofeeva, Maria
AU  - Farrington, Susan M
AU  - Jansen, Lina
AU  - Hemminki, Kari
AU  - Chang-Claude, Jenny
AU  - Brenner, Hermann
AU  - Hoffmeister, Michael
AU  - Dunlop, Malcolm G
AU  - Weber, Alexander N R
AU  - Försti, Asta
TI  - Coding variants in NOD-like receptors: An association study on risk and survival of colorectal cancer.
JO  - PLoS one
VL  - 13
IS  - 6
SN  - 1932-6203
CY  - Lawrence, Kan.
PB  - PLoS
M1  - DKFZ-2018-01176
SP  - e0199350 -
PY  - 2018
AB  - Nod-like receptors (NLRs) are important innate pattern recognition receptors and regulators of inflammation or play a role during development. We systematically analysed 41 non-synonymous single nucleotide polymorphisms (SNPs) in 21 NLR genes in a Czech discovery cohort of sporadic colorectal cancer (CRC) (1237 cases, 787 controls) for their association with CRC risk and survival. Five SNPs were found to be associated with CRC risk and eight with survival at 5
LB  - PUB:(DE-HGF)16
C6  - pmid:29928061
C2  - pmc:PMC6013205
DO  - DOI:10.1371/journal.pone.0199350
UR  - https://inrepo02.dkfz.de/record/136738
ER  -