% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Schmidt:136803,
      author       = {M. Schmidt$^*$ and J. Wiskemann and K. Steindorf$^*$},
      title        = {{Q}uality of life, problems, and needs of disease-free
                      breast cancer survivors 5 years after diagnosis.},
      journal      = {Quality of life research},
      volume       = {27},
      number       = {8},
      issn         = {1573-2649},
      address      = {Dordrecht [u.a.]},
      publisher    = {Springer Science + Business Media B.V},
      reportid     = {DKFZ-2018-01241},
      pages        = {2077 - 2086},
      year         = {2018},
      abstract     = {After cancer treatment, it is desirable to maintain or
                      regain a high quality of life (QoL) and the ability to
                      accomplish everyday tasks well. Therefore, we substantiated
                      the scarce knowledge regarding long-term QoL after breast
                      cancer, burdensome problems, and unmet needs for more
                      support.Disease-free breast cancer survivors (n = 190)
                      who had participated in two randomized controlled exercise
                      trials during primary treatment were followed up to 5 years
                      post-diagnosis. QoL-related functions and symptoms (EORTC
                      QLQ-C30/-BR23), health problems, and support needs were
                      assessed. EORTC-QLQ scores were compared with age-matched
                      normative values from the general population in
                      Germany.QoL-related functions and symptoms in patients
                      during cancer treatment were worse compared to healthy
                      references, but largely improved over time. Yet, cognitive
                      function and sleep were still significantly impaired at
                      5-year follow-up. Other common long-term problems included
                      sexual issues $(45\%$ of survivors), hot flashes $(38\%),$
                      pain $(34\%),$ fatigue $(24\%),$ and polyneuropathy
                      $(21\%).$ Regression analyses indicated fatigue having the
                      strongest impact on global QoL. Support needs were expressed
                      mainly for menopausal disorders $(43\%),$ physical
                      performance $(39\%),$ sleep problems $(38\%),$ arthralgia
                      $(37\%),$ cognitive problems $(36\%),$ weight problems
                      $(32\%),$ and fatigue $(31\%).While$ QoL in disease-free
                      breast cancer survivors 5 years post-diagnosis was largely
                      comparable to the general population on average, still many
                      survivors suffered from adverse effects. There appears to be
                      a need for ongoing screening and support regarding fatigue,
                      sleep problems, cognitive problems, arthralgia/pain,
                      menopausal/sexual symptoms, physical performance, and weight
                      problems during and several years following breast cancer
                      therapy.},
      cin          = {G210},
      ddc          = {100},
      cid          = {I:(DE-He78)G210-20160331},
      pnm          = {317 - Translational cancer research (POF3-317)},
      pid          = {G:(DE-HGF)POF3-317},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29740782},
      doi          = {10.1007/s11136-018-1866-8},
      url          = {https://inrepo02.dkfz.de/record/136803},
}