Home > Publications database > Quality of life, problems, and needs of disease-free breast cancer survivors 5 years after diagnosis. > print |
001 | 136803 | ||
005 | 20240229105100.0 | ||
024 | 7 | _ | |a 10.1007/s11136-018-1866-8 |2 doi |
024 | 7 | _ | |a pmid:29740782 |2 pmid |
024 | 7 | _ | |a 0962-9343 |2 ISSN |
024 | 7 | _ | |a 1573-2649 |2 ISSN |
024 | 7 | _ | |a altmetric:40869146 |2 altmetric |
037 | _ | _ | |a DKFZ-2018-01241 |
041 | _ | _ | |a eng |
082 | _ | _ | |a 100 |
100 | 1 | _ | |a Schmidt, Martina |0 P:(DE-He78)2def8f8594c8f797f5ed4398258c6cac |b 0 |e First author |
245 | _ | _ | |a Quality of life, problems, and needs of disease-free breast cancer survivors 5 years after diagnosis. |
260 | _ | _ | |a Dordrecht [u.a.] |c 2018 |b Springer Science + Business Media B.V |
336 | 7 | _ | |a article |2 DRIVER |
336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1539690417_27975 |2 PUB:(DE-HGF) |
336 | 7 | _ | |a ARTICLE |2 BibTeX |
336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
520 | _ | _ | |a After cancer treatment, it is desirable to maintain or regain a high quality of life (QoL) and the ability to accomplish everyday tasks well. Therefore, we substantiated the scarce knowledge regarding long-term QoL after breast cancer, burdensome problems, and unmet needs for more support.Disease-free breast cancer survivors (n = 190) who had participated in two randomized controlled exercise trials during primary treatment were followed up to 5 years post-diagnosis. QoL-related functions and symptoms (EORTC QLQ-C30/-BR23), health problems, and support needs were assessed. EORTC-QLQ scores were compared with age-matched normative values from the general population in Germany.QoL-related functions and symptoms in patients during cancer treatment were worse compared to healthy references, but largely improved over time. Yet, cognitive function and sleep were still significantly impaired at 5-year follow-up. Other common long-term problems included sexual issues (45% of survivors), hot flashes (38%), pain (34%), fatigue (24%), and polyneuropathy (21%). Regression analyses indicated fatigue having the strongest impact on global QoL. Support needs were expressed mainly for menopausal disorders (43%), physical performance (39%), sleep problems (38%), arthralgia (37%), cognitive problems (36%), weight problems (32%), and fatigue (31%).While QoL in disease-free breast cancer survivors 5 years post-diagnosis was largely comparable to the general population on average, still many survivors suffered from adverse effects. There appears to be a need for ongoing screening and support regarding fatigue, sleep problems, cognitive problems, arthralgia/pain, menopausal/sexual symptoms, physical performance, and weight problems during and several years following breast cancer therapy. |
536 | _ | _ | |a 317 - Translational cancer research (POF3-317) |0 G:(DE-HGF)POF3-317 |c POF3-317 |f POF III |x 0 |
588 | _ | _ | |a Dataset connected to CrossRef, PubMed, |
700 | 1 | _ | |a Wiskemann, Joachim |0 P:(DE-He78)60b584aeef81e4c57fd111fa63779b73 |b 1 |
700 | 1 | _ | |a Steindorf, Karen |0 P:(DE-He78)a0c2037d9054be26907a05ae520d5756 |b 2 |e Last author |
773 | _ | _ | |a 10.1007/s11136-018-1866-8 |g Vol. 27, no. 8, p. 2077 - 2086 |0 PERI:(DE-600)2008960-0 |n 8 |p 2077 - 2086 |t Quality of life research |v 27 |y 2018 |x 1573-2649 |
909 | C | O | |p VDB |o oai:inrepo02.dkfz.de:136803 |
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914 | 1 | _ | |y 2018 |
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