%0 Journal Article
%A Thöne, Kathrin
%A Rudolph, Anja
%A Obi, Nadia
%A Chang-Claude, Jenny
%A Flesch-Janys, Dieter
%T Prognostic impact of surgery for early-stage invasive breast cancer on breast cancer-specific survival, overall survival, and recurrence risk: a population-based analysis.
%J Breast cancer research and treatment
%V 170
%N 2
%@ 1573-7217
%C Dordrecht [u.a.]
%I Springer Science + Business Media B.V.
%M DKFZ-2018-01257
%P 381 - 390
%D 2018
%X Recent cohort studies demonstrated better overall survival (OS) or breast cancer-specific survival (BCS) for breast-conserving therapy (BCT) followed by radiation (RT) compared to mastectomy alone (MT). This is the first observational study in which adjustments for a comprehensive set of prognostic factors, adjuvant therapies, mode of detection, and comorbidities were possible to investigate OS, BCS, as well as recurrence risk of patients undergoing BCT + RT, MT + RT, or MT.Women aged 50-74 years at diagnosis of early-stage invasive breast cancer (I-IIIa) between 2001 and 2005 at the German population-based case-control study (MARIE study) were recruited and followed prospectively as a case cohort until 2015. Kaplan-Meier estimates and stepwise adjusted multivariable Cox models were used to estimate hazard ratios (HRs) and 95
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:29556781
%R 10.1007/s10549-018-4754-6
%U https://inrepo02.dkfz.de/record/136819