TY  - JOUR
AU  - Thöne, Kathrin
AU  - Rudolph, Anja
AU  - Obi, Nadia
AU  - Chang-Claude, Jenny
AU  - Flesch-Janys, Dieter
TI  - Prognostic impact of surgery for early-stage invasive breast cancer on breast cancer-specific survival, overall survival, and recurrence risk: a population-based analysis.
JO  - Breast cancer research and treatment
VL  - 170
IS  - 2
SN  - 1573-7217
CY  - Dordrecht [u.a.]
PB  - Springer Science + Business Media B.V.
M1  - DKFZ-2018-01257
SP  - 381 - 390
PY  - 2018
AB  - Recent cohort studies demonstrated better overall survival (OS) or breast cancer-specific survival (BCS) for breast-conserving therapy (BCT) followed by radiation (RT) compared to mastectomy alone (MT). This is the first observational study in which adjustments for a comprehensive set of prognostic factors, adjuvant therapies, mode of detection, and comorbidities were possible to investigate OS, BCS, as well as recurrence risk of patients undergoing BCT + RT, MT + RT, or MT.Women aged 50-74 years at diagnosis of early-stage invasive breast cancer (I-IIIa) between 2001 and 2005 at the German population-based case-control study (MARIE study) were recruited and followed prospectively as a case cohort until 2015. Kaplan-Meier estimates and stepwise adjusted multivariable Cox models were used to estimate hazard ratios (HRs) and 95
LB  - PUB:(DE-HGF)16
C6  - pmid:29556781
DO  - DOI:10.1007/s10549-018-4754-6
UR  - https://inrepo02.dkfz.de/record/136819
ER  -