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@ARTICLE{Zwanenburg:136844,
      author       = {A. Zwanenburg$^*$ and S. Löck$^*$},
      title        = {{W}hy validation of prognostic models matters?},
      journal      = {Radiotherapy and oncology},
      volume       = {127},
      number       = {3},
      issn         = {0167-8140},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {DKFZ-2018-01282},
      pages        = {370 - 373},
      year         = {2018},
      note         = {G947 NCT DD Liaison HZDR},
      abstract     = {Prognostic models are powerful tools for treatment
                      personalisation. However, not all proposed models work well
                      when validated using new data, despite impressive results
                      being reported initially. Here, we will use a hands-on
                      approach to highlight important aspects of prognostic
                      modelling, as well as to demonstrate methods to generate
                      generalisable models.},
      cin          = {L301 / G947},
      ddc          = {610},
      cid          = {I:(DE-He78)L301-20160331 / I:(DE-He78)G947-20160331},
      pnm          = {317 - Translational cancer research (POF3-317)},
      pid          = {G:(DE-HGF)POF3-317},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29598835},
      doi          = {10.1016/j.radonc.2018.03.004},
      url          = {https://inrepo02.dkfz.de/record/136844},
}