%0 Journal Article
%A Huang, Lei
%A Jansen, Lina
%A Balavarca, Yesilda
%A Babaei, Masoud
%A van der Geest, Lydia
%A Lemmens, Valery
%A Van Eycken, Liesbet
%A De Schutter, Harlinde
%A Johannesen, Tom B
%A Primic-Žakelj, Maja
%A Zadnik, Vesna
%A Besselink, Marc G
%A Schrotz-King, Petra
%A Brenner, Hermann
%T Stratified survival of resected and overall pancreatic cancer patients in Europe and the USA in the early twenty-first century: a large, international population-based study.
%J BMC medicine
%V 16
%N 1
%@ 1741-7015
%C London
%I BioMed Central
%M DKFZ-2018-01354
%P 125
%D 2018
%X The prognosis of pancreatic cancer (PaC) strongly varies across different stages and age groups, which has unfortunately not been well recorded in the literature. This international population-based study aimed to provide tumor-node-metastasis (TNM) stage- and age-specific survival estimates and trends in resected and overall (resected and unresected) PaC in the early twenty-first century.Using data from the US Surveillance, Epidemiology, and End Results-18 Program and the national cancer registries of the Netherlands, Belgium, Norway, and Slovenia, short-term and long-term overall survival results stratified by TNM stage and age in resected and overall primary PaC, irrespective of being microscopically confirmed or not, in 2003-2014 were computed using the Kaplan-Meier method. The temporal survival trends over three predefined periods (2003-2005, 2006-2008, and 2009-2011) were further examined using the log-rank test.In total, data for 125,183 patients were analyzed. Overall, age-stratified 3-year survival was 20-34
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:30126408
%2 pmc:PMC6102804
%R 10.1186/s12916-018-1120-9
%U https://inrepo02.dkfz.de/record/136916