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@ARTICLE{Sweegers:137585,
      author       = {M. G. Sweegers and T. M. Altenburg and J. Brug and A. M.
                      May and J. K. van Vulpen and N. K. Aaronson and G. Arbane
                      and M. Bohus and K. S. Courneya and A. J. Daley and D. A.
                      Galvao and R. Garrod and K. A. Griffith and W. H. Van Harten
                      and S. C. Hayes and F. Herrero-Román and M. J. Kersten and
                      A. Lucia and A. McConnachie and W. van Mechelen and N.
                      Mutrie and R. U. Newton and F. Nollet and K. Potthoff and M.
                      Schmidt$^*$ and K. H. Schmitz and K. H. Schulz and G. Sonke
                      and K. Steindorf$^*$ and M. M. Stuiver and D. R. Taaffe and
                      L. Thorsen and J. W. Twisk and M. J. Velthuis and J. Wenzel
                      and K. M. Winters-Stone and J. Wiskemann and M. J. Chin A
                      Paw and L. M. Buffart},
      title        = {{E}ffects and moderators of exercise on muscle strength,
                      muscle function and aerobic fitness in patients with cancer:
                      a meta-analysis of individual patient data.},
      journal      = {British journal of sports medicine},
      volume       = {53},
      number       = {13},
      issn         = {1473-0480},
      address      = {London},
      publisher    = {BMJ Publ. Group},
      reportid     = {DKFZ-2018-01465},
      pages        = {812},
      year         = {2019},
      abstract     = {To optimally target exercise interventions for patients
                      with cancer, it is important to identify which patients
                      benefit from which interventions.We conducted an individual
                      patient data meta-analysis to investigate demographic,
                      clinical, intervention-related and exercise-related
                      moderators of exercise intervention effects on physical
                      fitness in patients with cancer.We identified relevant
                      studies via systematic searches in electronic databases
                      (PubMed, Embase, PsycINFO and CINAHL).We analysed data from
                      28 randomised controlled trials investigating the effects of
                      exercise on upper body muscle strength (UBMS) and lower body
                      muscle strength (LBMS), lower body muscle function (LBMF)
                      and aerobic fitness in adult patients with cancer.Exercise
                      significantly improved UBMS (β=0.20, $95\%$ Confidence
                      Interval (CI) 0.14 to 0.26), LBMS (β=0.29, $95\%$ CI 0.23
                      to 0.35), LBMF (β=0.16, $95\%$ CI 0.08 to 0.24) and aerobic
                      fitness (β=0.28, $95\%$ CI 0.23 to 0.34), with larger
                      effects for supervised interventions. Exercise effects on
                      UBMS were larger during treatment, when supervised
                      interventions included ≥3 sessions per week, when
                      resistance exercises were included and when session duration
                      was >60 min. Exercise effects on LBMS were larger for
                      patients who were living alone, for supervised interventions
                      including resistance exercise and when session duration was
                      >60 min. Exercise effects on aerobic fitness were larger
                      for younger patients and when supervised interventions
                      included aerobic exercise.Exercise interventions during and
                      following cancer treatment had small effects on UBMS, LBMS,
                      LBMF and aerobic fitness. Demographic, intervention-related
                      and exercise-related characteristics including age, marital
                      status, intervention timing, delivery mode and frequency and
                      type and time of exercise sessions moderated the exercise
                      effect on UBMS, LBMS and aerobic fitness.},
      subtyp        = {Review Article},
      cin          = {C110},
      ddc          = {610},
      cid          = {I:(DE-He78)C110-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30181323},
      doi          = {10.1136/bjsports-2018-099191},
      url          = {https://inrepo02.dkfz.de/record/137585},
}