guest ::
| Home > Publications database > A novel superior medication-based chronic disease score (medCDS) predicted all-cause mortality in independent geriatric cohorts. > print |
| Home > Publications database > A novel superior medication-based chronic disease score (medCDS) predicted all-cause mortality in independent geriatric cohorts. > print |
| 001 | 137687 | ||
| 005 | 20240229112521.0 | ||
| 024 | 7 | _ | |a 10.1016/j.jclinepi.2018.09.004 |2 doi |
| 024 | 7 | _ | |a pmid:30253216 |2 pmid |
| 024 | 7 | _ | |a 0895-4356 |2 ISSN |
| 024 | 7 | _ | |a 1878-5921 |2 ISSN |
| 024 | 7 | _ | |a altmetric:48805796 |2 altmetric |
| 037 | _ | _ | |a DKFZ-2018-01564 |
| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Quinzler, R. |b 0 |
| 245 | _ | _ | |a A novel superior medication-based chronic disease score (medCDS) predicted all-cause mortality in independent geriatric cohorts. |
| 260 | _ | _ | |a Amsterdam [u.a.] |c 2019 |b Elsevier Science |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1551089095_18216 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a On the basis of current treatment guidelines, we developed and validated a medication-based chronic disease score (medCDS) and tested its association with all-cause mortality of older outpatients.Considering the most prevalent chronic diseases in the elderly German population, we compiled a list of evidence-based medicines used to treat these disorders. Based on this list, a score (medCDS) was developed to predict mortality using data of a large longitudinal cohort of older outpatients (training sample; MultiCare Cohort Study). By assessing receiver-operating characteristics (ROC curves), the performance of medCDS was then confirmed in independent cohorts (ESTHER, KORA-Age) of community-dwelling older patients and compared with already existing medication-based scores and a score using selected anatomical-therapeutic-chemical (ATC) codes.The final medCDS score had a ROC area-under-the-curve (AUC) of 0.73 (95 %-CI 0.70-0.76). In the validation cohorts, its ROC AUCs were 0.79 (0.76-0.82, KORA-Age) and 0.74 (0.71-0.78, ESTHER), which was superior to already existing medication-based scores (RxRisk, CDS) and scores based on pharmacological ATC code subgroups (ATC3) or age and sex alone (Age&Sex).A new medication-based chronic disease score (medCDS), which is based on actual treatment standards, predicts mortality of older outpatients significantly better than already existing scores. |
| 536 | _ | _ | |a 313 - Cancer risk factors and prevention (POF3-313) |0 G:(DE-HGF)POF3-313 |c POF3-313 |f POF III |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, |
| 700 | 1 | _ | |a Freitag, M. H. |b 1 |
| 700 | 1 | _ | |a Wiese, B. |b 2 |
| 700 | 1 | _ | |a Beyer, M. |b 3 |
| 700 | 1 | _ | |a Brenner, H. |0 P:(DE-He78)90d5535ff896e70eed81f4a4f6f22ae2 |b 4 |u dkfz |
| 700 | 1 | _ | |a Dahlhaus, A. |b 5 |
| 700 | 1 | _ | |a Döring, A. |b 6 |
| 700 | 1 | _ | |a Freund, T. |b 7 |
| 700 | 1 | _ | |a Heier, M. |b 8 |
| 700 | 1 | _ | |a Knopf, H. |b 9 |
| 700 | 1 | _ | |a Luppa, M. |b 10 |
| 700 | 1 | _ | |a Prokein, J. |b 11 |
| 700 | 1 | _ | |a Riedel-Heller, S. |b 12 |
| 700 | 1 | _ | |a Schäfer, I. |b 13 |
| 700 | 1 | _ | |a Scheidt-Nave, C. |b 14 |
| 700 | 1 | _ | |a Scherer, M. |b 15 |
| 700 | 1 | _ | |a Schöttker, B. |0 P:(DE-He78)c67a12496b8aac150c0eef888d808d46 |b 16 |u dkfz |
| 700 | 1 | _ | |a Szecsenyi, J. |b 17 |
| 700 | 1 | _ | |a Thürmann, P. |b 18 |
| 700 | 1 | _ | |a van den Bussche, H. |b 19 |
| 700 | 1 | _ | |a Gensichen, J. |b 20 |
| 700 | 1 | _ | |a Haefeli, W. E. |b 21 |
| 773 | _ | _ | |a 10.1016/j.jclinepi.2018.09.004 |g p. S0895435618302208 |0 PERI:(DE-600)1500490-9 |p 112-124 |t Journal of clinical epidemiology |v 105 |y 2019 |x 0895-4356 |
| 909 | C | O | |o oai:inrepo02.dkfz.de:137687 |p VDB |
| 910 | 1 | _ | |a Deutsches Krebsforschungszentrum |0 I:(DE-588b)2036810-0 |k DKFZ |b 4 |6 P:(DE-He78)90d5535ff896e70eed81f4a4f6f22ae2 |
| 910 | 1 | _ | |a Deutsches Krebsforschungszentrum |0 I:(DE-588b)2036810-0 |k DKFZ |b 16 |6 P:(DE-He78)c67a12496b8aac150c0eef888d808d46 |
| 913 | 1 | _ | |a DE-HGF |l Krebsforschung |1 G:(DE-HGF)POF3-310 |0 G:(DE-HGF)POF3-313 |2 G:(DE-HGF)POF3-300 |v Cancer risk factors and prevention |x 0 |4 G:(DE-HGF)POF |3 G:(DE-HGF)POF3 |b Gesundheit |
| 914 | 1 | _ | |y 2019 |
| 915 | _ | _ | |a Nationallizenz |0 StatID:(DE-HGF)0420 |2 StatID |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |b J CLIN EPIDEMIOL : 2015 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0600 |2 StatID |b Ebsco Academic Search |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b ASC |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Thomson Reuters Master Journal List |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0110 |2 StatID |b Science Citation Index |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0111 |2 StatID |b Science Citation Index Expanded |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1110 |2 StatID |b Current Contents - Clinical Medicine |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1030 |2 StatID |b Current Contents - Life Sciences |
| 915 | _ | _ | |a IF < 5 |0 StatID:(DE-HGF)9900 |2 StatID |
| 920 | 1 | _ | |0 I:(DE-He78)C070-20160331 |k C070 |l Klinische Epidemiologie und Alternsforschung |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-He78)C070-20160331 |
| 980 | _ | _ | |a UNRESTRICTED |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|