000140839 001__ 140839
000140839 005__ 20240229105117.0
000140839 0247_ $$2doi$$a10.1371/journal.pmed.1002651
000140839 0247_ $$2pmid$$apmid:30226842
000140839 0247_ $$2pmc$$apmc:PMC6143197
000140839 0247_ $$2ISSN$$a1549-1277
000140839 0247_ $$2ISSN$$a1549-1676
000140839 0247_ $$2altmetric$$aaltmetric:48598960
000140839 037__ $$aDKFZ-2018-01594
000140839 041__ $$aeng
000140839 082__ $$a610
000140839 1001_ $$00000-0002-3359-420X$$aDeschasaux, Mélanie$$b0
000140839 245__ $$aNutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study.
000140839 260__ $$aLawrence, Kan.$$bPLoS$$c2018
000140839 3367_ $$2DRIVER$$aarticle
000140839 3367_ $$2DataCite$$aOutput Types/Journal article
000140839 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1539608381_22566
000140839 3367_ $$2BibTeX$$aARTICLE
000140839 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000140839 3367_ $$00$$2EndNote$$aJournal Article
000140839 520__ $$aHelping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling system to reflect the nutritional quality of food products. The Nutri-Score, a five-colour nutrition label, is derived from the Nutrient Profiling System of the British Food Standards Agency (modified version) (FSAm-NPS). How the consumption of foods with high/low FSAm-NPS relates to cancer risk has been studied in national/regional cohorts but has not been characterized in diverse European populations.This prospective analysis included 471,495 adults from the European Prospective Investigation into Cancer and Nutrition (EPIC, 1992-2014, median follow-up: 15.3 y), among whom there were 49,794 incident cancer cases (main locations: breast, n = 12,063; prostate, n = 6,745; colon-rectum, n = 5,806). Usual food intakes were assessed with standardized country-specific diet assessment methods. The FSAm-NPS was calculated for each food/beverage using their 100-g content in energy, sugar, saturated fatty acid, sodium, fibres, proteins, and fruits/vegetables/legumes/nuts. The FSAm-NPS scores of all food items usually consumed by a participant were averaged to obtain the individual FSAm-NPS Dietary Index (DI) scores. Multi-adjusted Cox proportional hazards models were computed. A higher FSAm-NPS DI score, reflecting a lower nutritional quality of the food consumed, was associated with a higher risk of total cancer (HRQ5 versus Q1 = 1.07; 95% CI 1.03-1.10, P-trend < 0.001). Absolute cancer rates in those with high and low (quintiles 5 and 1) FSAm-NPS DI scores were 81.4 and 69.5 cases/10,000 person-years, respectively. Higher FSAm-NPS DI scores were specifically associated with higher risks of cancers of the colon-rectum, upper aerodigestive tract and stomach, lung for men, and liver and postmenopausal breast for women (all P < 0.05). The main study limitation is that it was based on an observational cohort using self-reported dietary data obtained through a single baseline food frequency questionnaire; thus, exposure misclassification and residual confounding cannot be ruled out.In this large multinational European cohort, the consumption of food products with a higher FSAm-NPS score (lower nutritional quality) was associated with a higher risk of cancer. This supports the relevance of the FSAm-NPS as underlying nutrient profiling system for front-of-pack nutrition labels, as well as for other public health nutritional measures.
000140839 536__ $$0G:(DE-HGF)POF3-313$$a313 - Cancer risk factors and prevention (POF3-313)$$cPOF3-313$$fPOF III$$x0
000140839 588__ $$aDataset connected to CrossRef, PubMed,
000140839 7001_ $$00000-0003-3838-855X$$aHuybrechts, Inge$$b1
000140839 7001_ $$00000-0003-3347-8249$$aMurphy, Neil$$b2
000140839 7001_ $$aJulia, Chantal$$b3
000140839 7001_ $$00000-0002-3168-1350$$aHercberg, Serge$$b4
000140839 7001_ $$00000-0002-1277-3380$$aSrour, Bernard$$b5
000140839 7001_ $$00000-0002-9715-3534$$aKesse-Guyot, Emmanuelle$$b6
000140839 7001_ $$aLatino-Martel, Paule$$b7
000140839 7001_ $$aBiessy, Carine$$b8
000140839 7001_ $$aCasagrande, Corinne$$b9
000140839 7001_ $$aJenab, Mazda$$b10
000140839 7001_ $$aWard, Heather$$b11
000140839 7001_ $$00000-0003-2237-0128$$aWeiderpass, Elisabete$$b12
000140839 7001_ $$00000-0003-0481-2893$$aDahm, Christina C$$b13
000140839 7001_ $$aOvervad, Kim$$b14
000140839 7001_ $$00000-0002-9083-8960$$aKyrø, Cecilie$$b15
000140839 7001_ $$00000-0003-4788-503X$$aOlsen, Anja$$b16
000140839 7001_ $$aAffret, Aurélie$$b17
000140839 7001_ $$00000-0002-5956-5693$$aBoutron-Ruault, Marie-Christine$$b18
000140839 7001_ $$00000-0002-5892-8886$$aMahamat-Saleh, Yahya$$b19
000140839 7001_ $$0P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a$$aKaaks, Rudolf$$b20$$udkfz
000140839 7001_ $$0P:(DE-He78)0907a10ba1dc8f53f04907f54f6fdcfe$$aKühn, Tilman$$b21$$udkfz
000140839 7001_ $$aBoeing, Heiner$$b22
000140839 7001_ $$aSchwingshackl, Lukas$$b23
000140839 7001_ $$aBamia, Christina$$b24
000140839 7001_ $$aPeppa, Eleni$$b25
000140839 7001_ $$aTrichopoulou, Antonia$$b26
000140839 7001_ $$aMasala, Giovanna$$b27
000140839 7001_ $$aKrogh, Vittorio$$b28
000140839 7001_ $$aPanico, Salvatore$$b29
000140839 7001_ $$00000-0003-2666-414X$$aTumino, Rosario$$b30
000140839 7001_ $$00000-0002-8008-5096$$aSacerdote, Carlotta$$b31
000140839 7001_ $$aBueno-de-Mesquita, Bas$$b32
000140839 7001_ $$aPeeters, Petra H$$b33
000140839 7001_ $$00000-0003-3002-4030$$aHjartåker, Anette$$b34
000140839 7001_ $$aRylander, Charlotta$$b35
000140839 7001_ $$00000-0003-2476-4251$$aSkeie, Guri$$b36
000140839 7001_ $$aRamón Quirós, J.$$b37
000140839 7001_ $$00000-0003-0672-8847$$aJakszyn, Paula$$b38
000140839 7001_ $$aSalamanca-Fernández, Elena$$b39
000140839 7001_ $$00000-0002-9637-3869$$aHuerta, José María$$b40
000140839 7001_ $$aArdanaz, Eva$$b41
000140839 7001_ $$aAmiano, Pilar$$b42
000140839 7001_ $$aEricson, Ulrika$$b43
000140839 7001_ $$00000-0002-0747-4562$$aSonestedt, Emily$$b44
000140839 7001_ $$aHuseinovic, Ena$$b45
000140839 7001_ $$00000-0002-9227-8434$$aJohansson, Ingegerd$$b46
000140839 7001_ $$aKhaw, Kay-Tee$$b47
000140839 7001_ $$00000-0003-1422-2993$$aWareham, Nick$$b48
000140839 7001_ $$00000-0003-3345-7333$$aBradbury, Kathryn E$$b49
000140839 7001_ $$00000-0002-5652-356X$$aPerez-Cornago, Aurora$$b50
000140839 7001_ $$aTsilidis, Konstantinos K$$b51
000140839 7001_ $$aFerrari, Pietro$$b52
000140839 7001_ $$00000-0001-6795-6080$$aRiboli, Elio$$b53
000140839 7001_ $$aGunter, Marc J$$b54
000140839 7001_ $$00000-0002-8322-8857$$aTouvier, Mathilde$$b55
000140839 773__ $$0PERI:(DE-600)2164823-2$$a10.1371/journal.pmed.1002651$$gVol. 15, no. 9, p. e1002651 -$$n9$$pe1002651 -$$tPLoS medicine$$v15$$x1549-1676$$y2018
000140839 909CO $$ooai:inrepo02.dkfz.de:140839$$pVDB
000140839 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a$$aDeutsches Krebsforschungszentrum$$b20$$kDKFZ
000140839 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)0907a10ba1dc8f53f04907f54f6fdcfe$$aDeutsches Krebsforschungszentrum$$b21$$kDKFZ
000140839 9131_ $$0G:(DE-HGF)POF3-313$$1G:(DE-HGF)POF3-310$$2G:(DE-HGF)POF3-300$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vCancer risk factors and prevention$$x0
000140839 9141_ $$y2018
000140839 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS
000140839 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline
000140839 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database
000140839 915__ $$0StatID:(DE-HGF)0320$$2StatID$$aDBCoverage$$bPubMed Central
000140839 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal
000140839 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ
000140839 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Peer review
000140839 915__ $$0LIC:(DE-HGF)CCBYNV$$2V:(DE-HGF)$$aCreative Commons Attribution CC BY (No Version)$$bDOAJ
000140839 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List
000140839 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded
000140839 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection
000140839 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine
000140839 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews
000140839 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bPLOS MED : 2017
000140839 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search
000140839 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC
000140839 915__ $$0StatID:(DE-HGF)9910$$2StatID$$aIF >= 10$$bPLOS MED : 2017
000140839 9201_ $$0I:(DE-He78)C020-20160331$$kC020$$lEpidemiologie von Krebserkrankungen$$x0
000140839 980__ $$ajournal
000140839 980__ $$aVDB
000140839 980__ $$aI:(DE-He78)C020-20160331
000140839 980__ $$aUNRESTRICTED