TY - JOUR AU - Deschasaux, Mélanie AU - Huybrechts, Inge AU - Murphy, Neil AU - Julia, Chantal AU - Hercberg, Serge AU - Srour, Bernard AU - Kesse-Guyot, Emmanuelle AU - Latino-Martel, Paule AU - Biessy, Carine AU - Casagrande, Corinne AU - Jenab, Mazda AU - Ward, Heather AU - Weiderpass, Elisabete AU - Dahm, Christina C AU - Overvad, Kim AU - Kyrø, Cecilie AU - Olsen, Anja AU - Affret, Aurélie AU - Boutron-Ruault, Marie-Christine AU - Mahamat-Saleh, Yahya AU - Kaaks, Rudolf AU - Kühn, Tilman AU - Boeing, Heiner AU - Schwingshackl, Lukas AU - Bamia, Christina AU - Peppa, Eleni AU - Trichopoulou, Antonia AU - Masala, Giovanna AU - Krogh, Vittorio AU - Panico, Salvatore AU - Tumino, Rosario AU - Sacerdote, Carlotta AU - Bueno-de-Mesquita, Bas AU - Peeters, Petra H AU - Hjartåker, Anette AU - Rylander, Charlotta AU - Skeie, Guri AU - Ramón Quirós, J. AU - Jakszyn, Paula AU - Salamanca-Fernández, Elena AU - Huerta, José María AU - Ardanaz, Eva AU - Amiano, Pilar AU - Ericson, Ulrika AU - Sonestedt, Emily AU - Huseinovic, Ena AU - Johansson, Ingegerd AU - Khaw, Kay-Tee AU - Wareham, Nick AU - Bradbury, Kathryn E AU - Perez-Cornago, Aurora AU - Tsilidis, Konstantinos K AU - Ferrari, Pietro AU - Riboli, Elio AU - Gunter, Marc J AU - Touvier, Mathilde TI - Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study. JO - PLoS medicine VL - 15 IS - 9 SN - 1549-1676 CY - Lawrence, Kan. PB - PLoS M1 - DKFZ-2018-01594 SP - e1002651 - PY - 2018 AB - Helping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling system to reflect the nutritional quality of food products. The Nutri-Score, a five-colour nutrition label, is derived from the Nutrient Profiling System of the British Food Standards Agency (modified version) (FSAm-NPS). How the consumption of foods with high/low FSAm-NPS relates to cancer risk has been studied in national/regional cohorts but has not been characterized in diverse European populations.This prospective analysis included 471,495 adults from the European Prospective Investigation into Cancer and Nutrition (EPIC, 1992-2014, median follow-up: 15.3 y), among whom there were 49,794 incident cancer cases (main locations: breast, n = 12,063; prostate, n = 6,745; colon-rectum, n = 5,806). Usual food intakes were assessed with standardized country-specific diet assessment methods. The FSAm-NPS was calculated for each food/beverage using their 100-g content in energy, sugar, saturated fatty acid, sodium, fibres, proteins, and fruits/vegetables/legumes/nuts. The FSAm-NPS scores of all food items usually consumed by a participant were averaged to obtain the individual FSAm-NPS Dietary Index (DI) scores. Multi-adjusted Cox proportional hazards models were computed. A higher FSAm-NPS DI score, reflecting a lower nutritional quality of the food consumed, was associated with a higher risk of total cancer (HRQ5 versus Q1 = 1.07; 95 LB - PUB:(DE-HGF)16 C6 - pmid:30226842 C2 - pmc:PMC6143197 DO - DOI:10.1371/journal.pmed.1002651 UR - https://inrepo02.dkfz.de/record/140839 ER -