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@ARTICLE{Freisling:141130,
      author       = {H. Freisling and H. Noh and N. Slimani and V. Chajès and
                      A. M. May and P. H. Peeters and E. Weiderpass and A. J.
                      Cross and G. Skeie and M. Jenab and F. R. Mancini and M.-C.
                      Boutron-Ruault and G. Fagherazzi and V. Katzke$^*$ and T.
                      Kühn$^*$ and A. Steffen and H. Boeing and A. Tjønneland
                      and C. Kyrø and C. P. Hansen and K. Overvad and E. J. Duell
                      and D. Redondo-Sánchez and P. Amiano and C. Navarro and A.
                      Barricarte and A. Perez-Cornago and K. K. Tsilidis and D.
                      Aune and H. Ward and A. Trichopoulou and A. Naska and P.
                      Orfanos and G. Masala and C. Agnoli and F. Berrino and R.
                      Tumino and C. Sacerdote and A. Mattiello and H. B.
                      Bueno-de-Mesquita and U. Ericson and E. Sonestedt and A.
                      Winkvist and T. Braaten and I. Romieu and J. Sabaté},
      title        = {{N}ut intake and 5-year changes in body weight and obesity
                      risk in adults: results from the {EPIC}-{PANACEA} study.},
      journal      = {European journal of nutrition},
      volume       = {57},
      number       = {7},
      issn         = {1436-6215},
      address      = {Heidelberg},
      publisher    = {Springer},
      reportid     = {DKFZ-2018-01661},
      pages        = {2399 - 2408},
      year         = {2018},
      abstract     = {There is inconsistent evidence regarding the relationship
                      between higher intake of nuts, being an energy-dense food,
                      and weight gain. We investigated the relationship between
                      nut intake and changes in weight over 5 years.This study
                      includes 373,293 men and women, 25-70 years old, recruited
                      between 1992 and 2000 from 10 European countries in the
                      European Prospective Investigation into Cancer and Nutrition
                      (EPIC) study. Habitual intake of nuts including peanuts,
                      together defined as nut intake, was estimated from
                      country-specific validated dietary questionnaires. Body
                      weight was measured at recruitment and self-reported
                      5 years later. The association between nut intake and body
                      weight change was estimated using multilevel mixed linear
                      regression models with center/country as random effect and
                      nut intake and relevant confounders as fixed effects. The
                      relative risk (RR) of becoming overweight or obese after
                      5 years was investigated using multivariate Poisson
                      regressions stratified according to baseline body mass index
                      (BMI).On average, study participants gained 2.1 kg (SD
                      5.0 kg) over 5 years. Compared to non-consumers, subjects
                      in the highest quartile of nut intake had less weight gain
                      over 5 years (-0.07 kg; $95\%$ CI -0.12 to -0.02) (P trend
                      = 0.025) and had $5\%$ lower risk of becoming overweight (RR
                      0.95; $95\%$ CI 0.92-0.98) or obese (RR 0.95; $95\%$ CI
                      0.90-0.99) (both P trend <0.008).Higher intake of nuts is
                      associated with reduced weight gain and a lower risk of
                      becoming overweight or obese.},
      cin          = {C020},
      ddc          = {610},
      cid          = {I:(DE-He78)C020-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:28733927},
      doi          = {10.1007/s00394-017-1513-0},
      url          = {https://inrepo02.dkfz.de/record/141130},
}