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@ARTICLE{Benzel:141151,
      author       = {J. Benzel$^*$ and V. Fendrich},
      title        = {{F}amilial {P}ancreatic {C}ancer.},
      journal      = {Oncology research and treatment},
      volume       = {41},
      number       = {10},
      issn         = {2296-5262},
      address      = {Basel},
      publisher    = {Karger},
      reportid     = {DKFZ-2018-01682},
      pages        = {611 - 618},
      year         = {2018},
      abstract     = {Familial pancreatic cancer accounts for $10\%$ of all
                      patients with pancreatic cancer. Because the 5-year survival
                      rate of pancreatic cancer is only $7\%,$ screening programs
                      for high-risk individuals are essential and might be
                      advantageous. Pancreatic ductal adenocarcinoma mostly shows
                      symptoms at an advanced state and treatment is not efficient
                      enough to cure most patients. People with hereditary tumor
                      syndromes or their affected relatives can also be included
                      in such screening programs. Besides the collection of data
                      to investigate the background of the disease, these
                      screening programs aim to diagnose and treat precursor
                      lesions so that more dangerous, invasive lesions are
                      prevented. These precursor lesions can be pancreatic
                      intraepithelial neoplasia, intraductal papillary mucinous
                      neoplasm, and mucinous cystic neoplasm. This review
                      summarizes the latest knowledge of pancreatic screening
                      programs, shows the procedure of pancreatic cancer
                      screening, and gives an overview of current guidelines.},
      subtyp        = {Review Article},
      cin          = {B062},
      ddc          = {350},
      cid          = {I:(DE-He78)B062-20160331},
      pnm          = {312 - Functional and structural genomics (POF3-312)},
      pid          = {G:(DE-HGF)POF3-312},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30269130},
      doi          = {10.1159/000493473},
      url          = {https://inrepo02.dkfz.de/record/141151},
}