%0 Journal Article
%A Bonekamp, David
%A Schelb, Patrick
%A Wiesenfarth, Manuel
%A Kuder, Tristan Anselm
%A Deister, Fenja
%A Stenzinger, Albrecht
%A Nyarangi-Dix, Joanne
%A Röthke, Matthias
%A Hohenfellner, Markus
%A Schlemmer, Heinz-Peter
%A Radtke, Jan Philipp
%T Histopathological to multiparametric MRI spatial mapping of extended systematic sextant and MR/TRUS-fusion-targeted biopsy of the prostate.
%J European radiology
%V 29
%N 4
%@ 1432-1084
%C Heidelberg
%I Springer
%M DKFZ-2018-01696
%P 1820-1830
%D 2019
%X MRI has limited ability to detect multifocal disease or the full extent of prostate involvement with clinically significant prostate cancer (sPC). We compare the spatial co-localization at sextant resolution of MRI lesions and histopathological mapping by combined targeted and extended systematic biopsies.Sextants were mapped for sPC (ISUP group ≥ 2) by 24-core transperineal systematic biopsies in 316 patients with suspicion for sPC and by MR lesions of PI-RADS score of ≥ 3. The gold standard is combined systematic (median 23 cores) and targeted biopsies.Of 316 men, 121 (38
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:30327861
%R 10.1007/s00330-018-5751-1
%U https://inrepo02.dkfz.de/record/141169