TY  - JOUR
AU  - Bonekamp, David
AU  - Schelb, Patrick
AU  - Wiesenfarth, Manuel
AU  - Kuder, Tristan Anselm
AU  - Deister, Fenja
AU  - Stenzinger, Albrecht
AU  - Nyarangi-Dix, Joanne
AU  - Röthke, Matthias
AU  - Hohenfellner, Markus
AU  - Schlemmer, Heinz-Peter
AU  - Radtke, Jan Philipp
TI  - Histopathological to multiparametric MRI spatial mapping of extended systematic sextant and MR/TRUS-fusion-targeted biopsy of the prostate.
JO  - European radiology
VL  - 29
IS  - 4
SN  - 1432-1084
CY  - Heidelberg
PB  - Springer
M1  - DKFZ-2018-01696
SP  - 1820-1830
PY  - 2019
AB  - MRI has limited ability to detect multifocal disease or the full extent of prostate involvement with clinically significant prostate cancer (sPC). We compare the spatial co-localization at sextant resolution of MRI lesions and histopathological mapping by combined targeted and extended systematic biopsies.Sextants were mapped for sPC (ISUP group ≥ 2) by 24-core transperineal systematic biopsies in 316 patients with suspicion for sPC and by MR lesions of PI-RADS score of ≥ 3. The gold standard is combined systematic (median 23 cores) and targeted biopsies.Of 316 men, 121 (38
LB  - PUB:(DE-HGF)16
C6  - pmid:30327861
DO  - DOI:10.1007/s00330-018-5751-1
UR  - https://inrepo02.dkfz.de/record/141169
ER  -