%0 Journal Article
%A Zamora-Ros, Raul
%A Cayssials, Valerie
%A Jenab, Mazda
%A Rothwell, Joseph A
%A Fedirko, Veronika
%A Aleksandrova, Krasimira
%A Tjønneland, Anne
%A Kyrø, Cecilie
%A Overvad, Kim
%A Boutron-Ruault, Marie-Christine
%A Carbonnel, Franck
%A Mahamat-Saleh, Yahya
%A Kaaks, Rudolf
%A Kühn, Tilman
%A Boeing, Heiner
%A Trichopoulou, Antonia
%A Valanou, Elissavet
%A Vasilopoulou, Effie
%A Masala, Giovanna
%A Pala, Valeria
%A Panico, Salvatore
%A Tumino, Rosario
%A Ricceri, Fulvio
%A Weiderpass, Elisabete
%A Lukic, Marko
%A Sandanger, Torkjel M
%A Lasheras, Cristina
%A Agudo, Antonio
%A Sánchez, Maria-Jose
%A Amiano, Pilar
%A Navarro, Carmen
%A Ardanaz, Eva
%A Sonestedt, Emily
%A Ohlsson, Bodil
%A Nilsson, Lena Maria
%A Rutegård, Martin
%A Bueno-de-Mesquita, Bas
%A Peeters, Petra H
%A Khaw, Kay-Thee
%A Wareham, Nicholas J
%A Bradbury, Kathryn
%A Freisling, Heinz
%A Romieu, Isabelle
%A Cross, Amanda J
%A Vineis, Paolo
%A Scalbert, Augustin
%T Dietary intake of total polyphenol and polyphenol classes and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.
%J European journal of epidemiology
%V 33
%N 11
%@ 1573-7284
%C Dordrecht [u.a.]
%I Springer Science + Business Media B.V.
%M DKFZ-2018-01780
%P 1063 - 1075
%D 2018
%X Polyphenols may play a chemopreventive role in colorectal cancer (CRC); however, epidemiological evidence supporting a role for intake of individual polyphenol classes, other than flavonoids is insufficient. We evaluated the association between dietary intakes of total and individual classes and subclasses of polyphenols and CRC risk and its main subsites, colon and rectum, within the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The cohort included 476,160 men and women from 10 European countries. During a mean follow-up of 14 years, there were 5991 incident CRC cases, of which 3897 were in the colon and 2094 were in the rectum. Polyphenol intake was estimated using validated centre/country specific dietary questionnaires and the Phenol-Explorer database. In multivariable-adjusted Cox regression models, a doubling in total dietary polyphenol intake was not associated with CRC risk in women (HRlog2 = 1.06, 95
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:29761424
%R 10.1007/s10654-018-0408-6
%U https://inrepo02.dkfz.de/record/141260